Polypharmacy and mortality among nursing home residents with advanced cognitive impairment: results from the SHELTER study

Graziano Onder; Rosa Liperoti; Andrea Foebel; Daniela Fialova; Eva Topinkova; Henriëtte G. Van Der Roest; Jacob Gindin; Alfonso J. Cruz-Jentoft; Massimo Fini; Giovanni Gambassi; Roberto Bernabei

doi:10.1016/j.jamda.2013.03.014

Polypharmacy and mortality among nursing home residents with advanced cognitive impairment: results from the SHELTER study

Graziano Onder, Rosa Liperoti, Andrea Foebel, Daniela Fialova, Eva Topinkova, Henriëtte G. Van Der Roest, Jacob Gindin, Alfonso J. Cruz-Jentoft, Massimo Fini, Giovanni Gambassi, Roberto Bernabei

Risultato della ricerca: Contributo in rivista › Articolo in rivista

84 Citazioni (Scopus)

Abstract

Older adults with advanced cognitive impairment have a limited life expectancy and the use of multiple drugs is of questionable benefit in this population. The aim of the present study was to assess if, in a sample of nursing home (NH) residents with advanced cognitive impairment, the effect of polypharmacy on mortality differs depending on estimated life expectancy.

Lingua originale	English
pagine (da-a)	450.e7-450.e7-12
Rivista	Journal of the American Medical Directors Association
Volume	14
DOI	https://doi.org/10.1016/j.jamda.2013.03.014
Stato di pubblicazione	Pubblicato - 2013

Keywords

Adrenergic beta-Antagonists
Aged
Aged, 80 and over
Anti-Bacterial Agents
Benzodiazepines
Cardiotonic Agents
Cognition Disorders
Digoxin
Drug Utilization
European Union
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Israel
Life Expectancy
Male
Nursing Homes
Polypharmacy

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10.1016/j.jamda.2013.03.014

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Onder, G., Liperoti, R., Foebel, A., Fialova, D., Topinkova, E., Van Der Roest, H. G., Gindin, J., Cruz-Jentoft, A. J., Fini, M., Gambassi, G., & Bernabei, R. (2013). Polypharmacy and mortality among nursing home residents with advanced cognitive impairment: results from the SHELTER study. Journal of the American Medical Directors Association, 14, 450.e7-450.e7-12. https://doi.org/10.1016/j.jamda.2013.03.014

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title = "Polypharmacy and mortality among nursing home residents with advanced cognitive impairment: results from the SHELTER study",

abstract = "Older adults with advanced cognitive impairment have a limited life expectancy and the use of multiple drugs is of questionable benefit in this population. The aim of the present study was to assess if, in a sample of nursing home (NH) residents with advanced cognitive impairment, the effect of polypharmacy on mortality differs depending on estimated life expectancy.",

keywords = "Adrenergic beta-Antagonists, Aged, Aged, 80 and over, Anti-Bacterial Agents, Benzodiazepines, Cardiotonic Agents, Cognition Disorders, Digoxin, Drug Utilization, European Union, Female, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Israel, Life Expectancy, Male, Nursing Homes, Polypharmacy, Adrenergic beta-Antagonists, Aged, Aged, 80 and over, Anti-Bacterial Agents, Benzodiazepines, Cardiotonic Agents, Cognition Disorders, Digoxin, Drug Utilization, European Union, Female, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Israel, Life Expectancy, Male, Nursing Homes, Polypharmacy",

author = "Graziano Onder and Rosa Liperoti and Andrea Foebel and Daniela Fialova and Eva Topinkova and {Van Der Roest}, {Henri{\"e}tte G.} and Jacob Gindin and Cruz-Jentoft, {Alfonso J.} and Massimo Fini and Giovanni Gambassi and Roberto Bernabei",

year = "2013",

doi = "10.1016/j.jamda.2013.03.014",

language = "English",

volume = "14",

pages = "450.e7--450.e7--12",

journal = "Journal of the American Medical Directors Association",

issn = "1538-9375",

publisher = "NEW YORK:ELSEVIER SCIENCE INC. Hagerstown, MD : Lippincott Williams & Wilkins, c2000-",

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Onder, G , Liperoti, R, Foebel, A, Fialova, D, Topinkova, E, Van Der Roest, HG, Gindin, J, Cruz-Jentoft, AJ, Fini, M, Gambassi, G & Bernabei, R 2013, 'Polypharmacy and mortality among nursing home residents with advanced cognitive impairment: results from the SHELTER study', Journal of the American Medical Directors Association, vol. 14, pagg. 450.e7-450.e7-12. https://doi.org/10.1016/j.jamda.2013.03.014

TY - JOUR

T1 - Polypharmacy and mortality among nursing home residents with advanced cognitive impairment: results from the SHELTER study

AU - Onder, Graziano

AU - Liperoti, Rosa

AU - Foebel, Andrea

AU - Fialova, Daniela

AU - Topinkova, Eva

AU - Van Der Roest, Henriëtte G.

AU - Gindin, Jacob

AU - Cruz-Jentoft, Alfonso J.

AU - Fini, Massimo

AU - Gambassi, Giovanni

AU - Bernabei, Roberto

PY - 2013

Y1 - 2013

N2 - Older adults with advanced cognitive impairment have a limited life expectancy and the use of multiple drugs is of questionable benefit in this population. The aim of the present study was to assess if, in a sample of nursing home (NH) residents with advanced cognitive impairment, the effect of polypharmacy on mortality differs depending on estimated life expectancy.

AB - Older adults with advanced cognitive impairment have a limited life expectancy and the use of multiple drugs is of questionable benefit in this population. The aim of the present study was to assess if, in a sample of nursing home (NH) residents with advanced cognitive impairment, the effect of polypharmacy on mortality differs depending on estimated life expectancy.

KW - Adrenergic beta-Antagonists

KW - Aged

KW - Aged, 80 and over

KW - Anti-Bacterial Agents

KW - Benzodiazepines

KW - Cardiotonic Agents

KW - Cognition Disorders

KW - Digoxin

KW - Drug Utilization

KW - European Union

KW - Female

KW - Humans

KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors

KW - Israel

KW - Life Expectancy

KW - Male

KW - Nursing Homes

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KW - Aged

KW - Aged, 80 and over

KW - Anti-Bacterial Agents

KW - Benzodiazepines

KW - Cardiotonic Agents

KW - Cognition Disorders

KW - Digoxin

KW - Drug Utilization

KW - European Union

KW - Female

KW - Humans

KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors

KW - Israel

KW - Life Expectancy

KW - Male

KW - Nursing Homes

KW - Polypharmacy

UR - http://hdl.handle.net/10807/51551

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M3 - Article

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VL - 14

SP - 450.e7-450.e7-12

JO - Journal of the American Medical Directors Association

JF - Journal of the American Medical Directors Association

ER -

Polypharmacy and mortality among nursing home residents with advanced cognitive impairment: results from the SHELTER study

Abstract

Keywords

OSS delle Nazioni Unite

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