Polymorphisms of the CYP1A1, CYP2E1 and XRCC1 genes and cancer risk in a Southern Italian population: a case-control study

Alessandro Sgambato, Gabriella Pompea Bianchino, Achille Renato Maria Cittadini, Viviana Grieco, Angela Zupa, Giuseppina Improta, Gabriella Bianchino, Vitina Grieco, Antonio Traficante, Michele Aieta

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

8 Citazioni (Scopus)

Abstract

Polymorphisms in genes encoding enzymes involved in xenobiotic metabolism and/or in cellular defenses against carcinogen-induced DNA damage play an important role in determining individual cancer susceptibility. However, their distribution and association with cancer susceptibility can vary in different populations.
Lingua originaleEnglish
pagine (da-a)1359-1365
Numero di pagine7
RivistaAnticancer Research
Volume31
Stato di pubblicazionePubblicato - 2011

Keywords

  • Adult
  • Aged
  • Case-Control Studies
  • Cytochrome P-450 CYP1A1
  • Cytochrome P-450 CYP2E1
  • DNA, Neoplasm
  • DNA-Binding Proteins
  • Female
  • Humans
  • Italy
  • Male
  • Middle Aged
  • Neoplasms
  • Polymerase Chain Reaction
  • Polymorphism, Genetic
  • Polymorphism, Restriction Fragment Length

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