Polyclonal serum-free light chains elevation in HIV-infected patients

Simona Di Giambenedetto, M Bibas, P Lorenzini, A Cozzi Lepri, A Calcagno, A Costantini, A Castagna, V Manfrin, Ad Monforte, A. Antinori

Risultato della ricerca: Contributo in rivistaArticolo in rivista

9 Citazioni (Scopus)

Abstract

We investigated the association between polyclonal serum-free light chains and prognostic biomarkers routinely used in the setting of HIV infection. For this purpose serum samples of 182 HIV-infected patients from the Italian Cohort of Antiretroviral Naive Patients foundation cohort were analysed. We found that polyclonal serum free light chains above the upper normal limit are strongly correlated in HIV-infected patients with advancing age, shorter time of undetectable HIV viremia, higher viral load and with lower CD4 cell count at sample.
Lingua originaleEnglish
pagine (da-a)2107-2110
Numero di pagine4
RivistaAIDS
Volume26
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • Polyclonal light chains , HIV

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