Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance"

F Santilli; Bianca Rocca; Raimondo De Cristofaro; S Lattanzio; L Pietrangelo; A Habib; C Pettinella; A Recchiuti; E Ferrante; G Ciabattoni; G Davì; Carlo Patrono

doi:10.1016/j.jacc.2008.10.047

Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance"

F Santilli
, Bianca Rocca
, Raimondo De Cristofaro
, S Lattanzio
, L Pietrangelo
, A Habib
, C Pettinella
, A Recchiuti
, E Ferrante
, G Ciabattoni
, G Davì
, Carlo Patrono

Risultato della ricerca: Contributo in rivista › Articolo

209 Citazioni (Scopus)

Abstract

This study was conducted to assess the thromboxane (TX) dependence of biochemical and functional indexes used to monitor the effect of low-dose aspirin.

Lingua originale	Inglese
pagine (da-a)	667-677
Numero di pagine	11
Rivista	Journal of the American College of Cardiology
Volume	53
Numero di pubblicazione	8
DOI	https://doi.org/10.1016/j.jacc.2008.10.047
Stato di pubblicazione	Pubblicato - 2009

Keywords

Adenosine Diphosphate
Adult
Aspirin
Blood Platelets
Cyclooxygenase 2
Cyclooxygenase Inhibitors
Drug Resistance
Female
Humans
Male
Platelet Aggregation
Platelet Aggregation Inhibitors
Platelet Function Tests
Thrombopoietin
Thromboxane B2
Young Adult

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10.1016/j.jacc.2008.10.047

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Santilli, F., Rocca, B., De Cristofaro, R., Lattanzio, S., Pietrangelo, L., Habib, A., Pettinella, C., Recchiuti, A., Ferrante, E., Ciabattoni, G., Davì, G., & Patrono, C. (2009). Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance". Journal of the American College of Cardiology, 53(8), 667-677. https://doi.org/10.1016/j.jacc.2008.10.047

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title = "Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin {"}resistance{"}",

abstract = "This study was conducted to assess the thromboxane (TX) dependence of biochemical and functional indexes used to monitor the effect of low-dose aspirin.",

keywords = "Adenosine Diphosphate, Adult, Aspirin, Blood Platelets, Cyclooxygenase 2, Cyclooxygenase Inhibitors, Drug Resistance, Female, Humans, Male, Platelet Aggregation, Platelet Aggregation Inhibitors, Platelet Function Tests, Thrombopoietin, Thromboxane B2, Young Adult, Adenosine Diphosphate, Adult, Aspirin, Blood Platelets, Cyclooxygenase 2, Cyclooxygenase Inhibitors, Drug Resistance, Female, Humans, Male, Platelet Aggregation, Platelet Aggregation Inhibitors, Platelet Function Tests, Thrombopoietin, Thromboxane B2, Young Adult",

author = "F Santilli and Bianca Rocca and \{De Cristofaro\}, Raimondo and S Lattanzio and L Pietrangelo and A Habib and C Pettinella and A Recchiuti and E Ferrante and G Ciabattoni and G Dav{\`i} and Carlo Patrono",

year = "2009",

doi = "10.1016/j.jacc.2008.10.047",

language = "English",

volume = "53",

pages = "667--677",

journal = "Journal of the American College of Cardiology",

issn = "0735-1097",

publisher = "Elsevier Inc.",

number = "8",

}

Santilli, F, Rocca, B, De Cristofaro, R, Lattanzio, S, Pietrangelo, L, Habib, A, Pettinella, C, Recchiuti, A, Ferrante, E, Ciabattoni, G, Davì, G & Patrono, C 2009, 'Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance"', Journal of the American College of Cardiology, vol. 53, n. 8, pagg. 667-677. https://doi.org/10.1016/j.jacc.2008.10.047

TY - JOUR

T1 - Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance"

AU - Santilli, F

AU - Rocca, Bianca

AU - De Cristofaro, Raimondo

AU - Lattanzio, S

AU - Pietrangelo, L

AU - Habib, A

AU - Pettinella, C

AU - Recchiuti, A

AU - Ferrante, E

AU - Ciabattoni, G

AU - Davì, G

AU - Patrono, Carlo

PY - 2009

Y1 - 2009

N2 - This study was conducted to assess the thromboxane (TX) dependence of biochemical and functional indexes used to monitor the effect of low-dose aspirin.

AB - This study was conducted to assess the thromboxane (TX) dependence of biochemical and functional indexes used to monitor the effect of low-dose aspirin.

KW - Adenosine Diphosphate

KW - Adult

KW - Aspirin

KW - Blood Platelets

KW - Cyclooxygenase 2

KW - Cyclooxygenase Inhibitors

KW - Drug Resistance

KW - Female

KW - Humans

KW - Male

KW - Platelet Aggregation

KW - Platelet Aggregation Inhibitors

KW - Platelet Function Tests

KW - Thrombopoietin

KW - Thromboxane B2

KW - Young Adult

KW - Adenosine Diphosphate

KW - Adult

KW - Aspirin

KW - Blood Platelets

KW - Cyclooxygenase 2

KW - Cyclooxygenase Inhibitors

KW - Drug Resistance

KW - Female

KW - Humans

KW - Male

KW - Platelet Aggregation

KW - Platelet Aggregation Inhibitors

KW - Platelet Function Tests

KW - Thrombopoietin

KW - Thromboxane B2

KW - Young Adult

UR - https://publicatt.unicatt.it/handle/10807/25332

U2 - 10.1016/j.jacc.2008.10.047

DO - 10.1016/j.jacc.2008.10.047

M3 - Article

SN - 0735-1097

VL - 53

SP - 667

EP - 677

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

IS - 8

ER -

Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance"

Abstract

Keywords

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