Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance"

Bianca Rocca, Raimondo De Cristofaro, Carlo Patrono, F Santilli, S Lattanzio, L Pietrangelo, A Habib, C Pettinella, A Recchiuti, E Ferrante, G Ciabattoni, G Davì

Risultato della ricerca: Contributo in rivistaArticolo in rivista

209 Citazioni (Scopus)

Abstract

This study was conducted to assess the thromboxane (TX) dependence of biochemical and functional indexes used to monitor the effect of low-dose aspirin.
Lingua originaleEnglish
pagine (da-a)667-677
Numero di pagine11
RivistaJOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Volume53
DOI
Stato di pubblicazionePubblicato - 2009

Keywords

  • Adenosine Diphosphate
  • Adult
  • Aspirin
  • Blood Platelets
  • Cyclooxygenase 2
  • Cyclooxygenase Inhibitors
  • Drug Resistance
  • Female
  • Humans
  • Male
  • Platelet Aggregation
  • Platelet Aggregation Inhibitors
  • Platelet Function Tests
  • Thrombopoietin
  • Thromboxane B2
  • Young Adult

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