Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance"

F Santilli, Bianca Rocca, Raimondo De Cristofaro, S Lattanzio, L Pietrangelo, A Habib, C Pettinella, A Recchiuti, E Ferrante, G Ciabattoni, G Davì, Carlo Patrono

Risultato della ricerca: Contributo in rivistaArticolo

209 Citazioni (Scopus)

Abstract

This study was conducted to assess the thromboxane (TX) dependence of biochemical and functional indexes used to monitor the effect of low-dose aspirin.
Lingua originaleInglese
pagine (da-a)667-677
Numero di pagine11
RivistaJournal of the American College of Cardiology
Volume53
Numero di pubblicazione8
DOI
Stato di pubblicazionePubblicato - 2009

Keywords

  • Adenosine Diphosphate
  • Adult
  • Aspirin
  • Blood Platelets
  • Cyclooxygenase 2
  • Cyclooxygenase Inhibitors
  • Drug Resistance
  • Female
  • Humans
  • Male
  • Platelet Aggregation
  • Platelet Aggregation Inhibitors
  • Platelet Function Tests
  • Thrombopoietin
  • Thromboxane B2
  • Young Adult

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