TY - JOUR
T1 - Photodynamic therapy with 5-aminolevulinate patch for the treatment of superficial basal cell carcinomas
AU - De, Luca E. V.
AU - Tambone, S.
AU - Catapano, S.
AU - Fossati, B.
AU - Peris, Ketty
PY - 2020
Y1 - 2020
N2 - 5-Aminolevulinate (ALA) patches with red light (630-nm light source and a total light dose of 37 J/cm2) is an effective treatment indicated by food and drug administration (FDA) and european medicines agency (EMA) only for grade I to II actinic keratosis located on the scalp and face. Currently, there are no efficacy data on their use in the treatment of other types of epithelial neoplasms. We analyzed the efficacy of ALA patches in seven superficial basal cell carcinomas (sBCCs) that occurred in four patients. All lesions were treated with topical ALA patches. A complete response of all sBCCs was achieved at week 24 after treatment. Our study suggests that ALA patches for sBCCs have good efficacy rates and excellent safety profile.
AB - 5-Aminolevulinate (ALA) patches with red light (630-nm light source and a total light dose of 37 J/cm2) is an effective treatment indicated by food and drug administration (FDA) and european medicines agency (EMA) only for grade I to II actinic keratosis located on the scalp and face. Currently, there are no efficacy data on their use in the treatment of other types of epithelial neoplasms. We analyzed the efficacy of ALA patches in seven superficial basal cell carcinomas (sBCCs) that occurred in four patients. All lesions were treated with topical ALA patches. A complete response of all sBCCs was achieved at week 24 after treatment. Our study suggests that ALA patches for sBCCs have good efficacy rates and excellent safety profile.
KW - 5-aminolevulinate patch
KW - basal cell carcinoma
KW - photodynamic therapy
KW - 5-aminolevulinate patch
KW - basal cell carcinoma
KW - photodynamic therapy
UR - https://publicatt.unicatt.it/handle/10807/168702
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85096759290&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85096759290&origin=inward
U2 - 10.1111/dth.14518
DO - 10.1111/dth.14518
M3 - Article
SN - 1396-0296
VL - 33
SP - e14518-N/A
JO - Dermatologic Therapy
JF - Dermatologic Therapy
IS - 6
ER -