Duplications of chromosome 15 have been reported in individuals with atypical autism, varying degrees of mental retardation, and epilepsy. The authors report the molecular analysis, neurophysiologic, and clinical evaluation of a 12-year-old boy with atypical autism and epilepsy due to a maternally derived 15q11-q13 duplication. Their findings suggest that this chromosomal region harbors genes for autism and possibly for partial epilepsy that may act in a dose-dependent manner.
|Numero di pagine||4|
|Stato di pubblicazione||Pubblicato - 1999|
- Child Development Disorders, Pervasive
- Chromosomes, Human, Pair 15
- Gene Duplication