TY - JOUR
T1 - Peritoneal carcinomatosis from advanced ovarian cancer:To treat or not to treat ethical issues suggested by a case study
AU - Nicoti, Mirco
AU - Colombetti, Elena
AU - Spada, Maria Simonetta
AU - Ceresoli, Marco
AU - Ansaloni, Luca
AU - Marchesi, Gianmariano
AU - Lorini, Luca
AU - Corbella, Davide
AU - Coccolini, Federico
PY - 2014
Y1 - 2014
N2 - This article provides a brief description of an Epithelial Ovarian Cancer (EOC) case (stage Ⅳ) treated with the association of complete CytoReductive Surgery and Hypertermic IntraPEritoneal Chemotherapy (HIPEC). The use of HIPEC in EOC makes theoretic sense in view of the high rates of recurrence following standard treatment,
but there are no randomized clinical trial to date and HIPEC for these patients still represents a radical
treatment where the choice of no treatment may be acceptable since definitive cure is unlikely. We reviewed
the entire decision making process considering the risk/benefit of the procedure in term of mortality/morbidity,
the quality of life and the psychological profile of the
patient 1 year after surgery. The platform World Health
Organization- International Classification of Functioning,
Disability and Health that permits evaluation of the
person in relation to the psycho-social context is presented.
A person-centred approach and assessment of health-related quality-of-life and disability in EOC survivors are of central importance for decision making.
AB - This article provides a brief description of an Epithelial Ovarian Cancer (EOC) case (stage Ⅳ) treated with the association of complete CytoReductive Surgery and Hypertermic IntraPEritoneal Chemotherapy (HIPEC). The use of HIPEC in EOC makes theoretic sense in view of the high rates of recurrence following standard treatment,
but there are no randomized clinical trial to date and HIPEC for these patients still represents a radical
treatment where the choice of no treatment may be acceptable since definitive cure is unlikely. We reviewed
the entire decision making process considering the risk/benefit of the procedure in term of mortality/morbidity,
the quality of life and the psychological profile of the
patient 1 year after surgery. The platform World Health
Organization- International Classification of Functioning,
Disability and Health that permits evaluation of the
person in relation to the psycho-social context is presented.
A person-centred approach and assessment of health-related quality-of-life and disability in EOC survivors are of central importance for decision making.
KW - Advanced epithelial ovarian cancer
KW - Disability and Health
KW - Ethical issues
KW - Health related quality of life
KW - Hyperthemic intraperitoneal chemotherapy
KW - International Classification of Functioning
KW - Advanced epithelial ovarian cancer
KW - Disability and Health
KW - Ethical issues
KW - Health related quality of life
KW - Hyperthemic intraperitoneal chemotherapy
KW - International Classification of Functioning
UR - http://hdl.handle.net/10807/51467
M3 - Article
SN - 2218-6220
SP - 14
EP - 20
JO - WORLD JOURNAL OF OBSTETRICS AND GYNECOLOGY
JF - WORLD JOURNAL OF OBSTETRICS AND GYNECOLOGY
ER -