Peristeen transanal irrigation in paediatric patiens with anorectal malformations and spinal cord lesions: a multicentre Italian study.

Claudia Rendeli, Emanuele Ausili, Piergiorgio Gamba, Lido Lombardi, P. Midrio, G. Mosiello, P. Gamba, A. Marte, L. Lombardi, B. D. Iacobelli, E. Caponcelli, S. Marrello, M. Meroni, G. Brisighelli, E. Leva

Risultato della ricerca: Contributo in rivistaArticolo in rivista

22 Citazioni (Scopus)


AIM: In paediatric and adult patients with neurogenic bowel, transanal irrigation (TAI) of the colon has gained popularity due to the introduction of a specifically designed device. The aim of this pilot study was to present the results of TAI using the Peristeen(®) TAI system in a group of paediatric patients with anorectal malformation (ARM) and congenital or acquired spinal cord lesions (SCLs). METHOD: Eight Italian paediatric surgery and spina bifida centres participated in the study. The inclusion criteria were age between 6 and 17 years, weight above 20 kg and unsatisfactory bowel management. Patients with chronic inflammatory bowel disease, mental disability and surgery within the previous 3 months were excluded. At the beginning of treatment (T0) and after 3 months (T1) the Bristol scale, a questionnaire assessing bowel function, and two questionnaires on quality of life (QoL) for patients aged 6-11 years (CHQ-pf50) and 12-17 years (SF36) were administered. RESULTS: Eighty-three patients were enrolled, and seventy-eight completed the study (41 ARMs, 37 SCLs). At T1, constipation was reduced in ARMs from 69% to 25.6% and in SCLs from 92.7% to 41.5%, faecal incontinence in ARMs from 50% to 18.6% and in SCLs from 39% to 9.8% and flatus incontinence in ARMs from 20.9% to 9.8% and in SCLs from 31.7% to 10%. At T0, the Bristol Stool Scale types were 1-2 in 45% of ARMs and 77.5% of SCL patients, whereas at T1 types 1-2 were recorded in only 2.5% of SCL patients. QoL improved in both groups. In the younger group, a significant improvement in QoL was recorded in ARM patients for eight of nine variables and in SCL patients for seven of nine variables. CONCLUSION: This study showed that Peristeen TAI resulted in a significant time reduction in colonic cleansing, increased independence from the carer and improved QoL in paediatric patients with ARMs and SCLs.
Lingua originaleEnglish
pagine (da-a)86-93
Numero di pagine8
RivistaColorectal Disease
Stato di pubblicazionePubblicato - 2016


  • Anorectal malformations
  • Bowel dysfunction
  • Enema
  • Peristeen
  • Spinal cord injures
  • Transanal irrigation


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