Perioperative HDR brachytherapy for reirradiation in head and neck recurrences: Single-institution experience and systematic review

Luca Tagliaferri; Francesco Bussu; Bruno Fionda; Francesco Catucci; Mario Rigante; Maria Antonietta Gambacorta; Rosa Autorino; Gian Carlo Mattiucci; Francesco Micciche'; Elisa Placidi; Mario Balducci; Jacopo Galli; Gaetano Paludetti; György Kovacs; Vincenzo Valentini

doi:10.5301/tj.5000614

Perioperative HDR brachytherapy for reirradiation in head and neck recurrences: Single-institution experience and systematic review

Luca Tagliaferri, Francesco Bussu, Bruno Fionda, Francesco Catucci, Mario Rigante, Maria Antonietta Gambacorta, Rosa Autorino, Gian Carlo Mattiucci, Francesco Micciche', Elisa Placidi, Mario Balducci, Jacopo Galli, Gaetano Paludetti, György Kovacs, Vincenzo Valentini

Universitätsklinikum Schleswig-Holstein Campus Lübeck

Risultato della ricerca: Contributo in rivista › Articolo in rivista

15 Citazioni (Scopus)

Abstract

Aim: The aim of our study was to evaluate the outcomes of patients reirradiated with high-dose-rate (HDR) intensity-modulated brachytherapy (IMBT) for recurrent head and neck cancer and to perform a systematic review of the literature. Materials and methods: Patients treated with prior radiation doses > 65 Gy were considered. After resection of macroscopic disease, catheters were fixed to the tumor bed. The total dose was 30 Gy in 12 fractions of 2.5 Gy twice daily for 5 days a week. A systematic literature search was conducted through several electronic databases including Medline/PubMed, Scopus, Embase and the Cochrane library. Results: Seventeen patients were included; median overall survival was 19 months with a median local control interval of 15 months. Median follow-up was 36 months. Seven papers were considered for the review. Conclusions: IMBT could play an important role in the retreatment of recurrent head and neck cancer.

Lingua originale	English
pagine (da-a)	516-524
Numero di pagine	9
Rivista	Tumori
Volume	103
DOI	https://doi.org/10.5301/tj.5000614
Stato di pubblicazione	Pubblicato - 2017

Keywords

Brachytherapy
Cancer Research
Female
HDR
Head and Neck Neoplasms
Head and neck cancer
Humans
Male
Neoplasm Recurrence, Local
Oncology
Radiotherapy
Radiotherapy, Intensity-Modulated
Re-Irradiation
Recurrence

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Tagliaferri, L., Bussu, F., Fionda, B., Catucci, F., Rigante, M., Gambacorta, M. A., Autorino, R., Mattiucci, G. C., Micciche', F., Placidi, E., Balducci, M., Galli, J., Paludetti, G., Kovacs, G., & Valentini, V. (2017). Perioperative HDR brachytherapy for reirradiation in head and neck recurrences: Single-institution experience and systematic review. Tumori, 103, 516-524. https://doi.org/10.5301/tj.5000614

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title = "Perioperative HDR brachytherapy for reirradiation in head and neck recurrences: Single-institution experience and systematic review",

abstract = "Aim: The aim of our study was to evaluate the outcomes of patients reirradiated with high-dose-rate (HDR) intensity-modulated brachytherapy (IMBT) for recurrent head and neck cancer and to perform a systematic review of the literature. Materials and methods: Patients treated with prior radiation doses > 65 Gy were considered. After resection of macroscopic disease, catheters were fixed to the tumor bed. The total dose was 30 Gy in 12 fractions of 2.5 Gy twice daily for 5 days a week. A systematic literature search was conducted through several electronic databases including Medline/PubMed, Scopus, Embase and the Cochrane library. Results: Seventeen patients were included; median overall survival was 19 months with a median local control interval of 15 months. Median follow-up was 36 months. Seven papers were considered for the review. Conclusions: IMBT could play an important role in the retreatment of recurrent head and neck cancer.",

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author = "Luca Tagliaferri and Francesco Bussu and Bruno Fionda and Francesco Catucci and Mario Rigante and Gambacorta, {Maria Antonietta} and Rosa Autorino and Mattiucci, {Gian Carlo} and Francesco Micciche' and Elisa Placidi and Mario Balducci and Jacopo Galli and Gaetano Paludetti and Gy{\"o}rgy Kovacs and Vincenzo Valentini",

year = "2017",

doi = "10.5301/tj.5000614",

language = "English",

volume = "103",

pages = "516--524",

journal = "Tumori",

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Tagliaferri, L, Bussu, F, Fionda, B, Catucci, F, Rigante, M, Gambacorta, MA, Autorino, R, Mattiucci, GC, Micciche', F, Placidi, E, Balducci, M, Galli, J, Paludetti, G, Kovacs, G & Valentini, V 2017, 'Perioperative HDR brachytherapy for reirradiation in head and neck recurrences: Single-institution experience and systematic review', Tumori, vol. 103, pagg. 516-524. https://doi.org/10.5301/tj.5000614

TY - JOUR

T1 - Perioperative HDR brachytherapy for reirradiation in head and neck recurrences: Single-institution experience and systematic review

AU - Tagliaferri, Luca

AU - Bussu, Francesco

AU - Fionda, Bruno

AU - Catucci, Francesco

AU - Rigante, Mario

AU - Gambacorta, Maria Antonietta

AU - Autorino, Rosa

AU - Mattiucci, Gian Carlo

AU - Micciche', Francesco

AU - Placidi, Elisa

AU - Balducci, Mario

AU - Galli, Jacopo

AU - Paludetti, Gaetano

AU - Kovacs, György

AU - Valentini, Vincenzo

PY - 2017

Y1 - 2017

N2 - Aim: The aim of our study was to evaluate the outcomes of patients reirradiated with high-dose-rate (HDR) intensity-modulated brachytherapy (IMBT) for recurrent head and neck cancer and to perform a systematic review of the literature. Materials and methods: Patients treated with prior radiation doses > 65 Gy were considered. After resection of macroscopic disease, catheters were fixed to the tumor bed. The total dose was 30 Gy in 12 fractions of 2.5 Gy twice daily for 5 days a week. A systematic literature search was conducted through several electronic databases including Medline/PubMed, Scopus, Embase and the Cochrane library. Results: Seventeen patients were included; median overall survival was 19 months with a median local control interval of 15 months. Median follow-up was 36 months. Seven papers were considered for the review. Conclusions: IMBT could play an important role in the retreatment of recurrent head and neck cancer.

AB - Aim: The aim of our study was to evaluate the outcomes of patients reirradiated with high-dose-rate (HDR) intensity-modulated brachytherapy (IMBT) for recurrent head and neck cancer and to perform a systematic review of the literature. Materials and methods: Patients treated with prior radiation doses > 65 Gy were considered. After resection of macroscopic disease, catheters were fixed to the tumor bed. The total dose was 30 Gy in 12 fractions of 2.5 Gy twice daily for 5 days a week. A systematic literature search was conducted through several electronic databases including Medline/PubMed, Scopus, Embase and the Cochrane library. Results: Seventeen patients were included; median overall survival was 19 months with a median local control interval of 15 months. Median follow-up was 36 months. Seven papers were considered for the review. Conclusions: IMBT could play an important role in the retreatment of recurrent head and neck cancer.

KW - Brachytherapy

KW - Cancer Research

KW - Female

KW - HDR

KW - Head and Neck Neoplasms

KW - Head and neck cancer

KW - Humans

KW - Male

KW - Neoplasm Recurrence, Local

KW - Oncology

KW - Radiotherapy

KW - Radiotherapy, Intensity-Modulated

KW - Re-Irradiation

KW - Recurrence

KW - Brachytherapy

KW - Cancer Research

KW - Female

KW - HDR

KW - Head and Neck Neoplasms

KW - Head and neck cancer

KW - Humans

KW - Male

KW - Neoplasm Recurrence, Local

KW - Oncology

KW - Radiotherapy

KW - Radiotherapy, Intensity-Modulated

KW - Re-Irradiation

KW - Recurrence

UR - http://hdl.handle.net/10807/111892

UR - http://www.tumorijournal.com/attach/824d4963-5c84-4790-b5f2-819255310e68/38af0f51-34d7-42f5-8949-064b0e97a718

U2 - 10.5301/tj.5000614

DO - 10.5301/tj.5000614

M3 - Article

SN - 0300-8916

VL - 103

SP - 516

EP - 524

JO - Tumori

JF - Tumori

ER -

Perioperative HDR brachytherapy for reirradiation in head and neck recurrences: Single-institution experience and systematic review

Abstract

Keywords

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