Performance of cardiac cadmium-zinc-telluride gamma camera imaging in coronary artery disease: a review from the cardiovascular committee of the European Association of Nuclear Medicine (EANM)

Alessandro Giordano, Denis Agostini, Pierre-Yves Marie, Simona Ben-Haim, François Rouzet, Bernard Songy, Alessia Gimelli, Fabien Hyafil, Roberto Sciagrà, Jan Bucerius, Hein J. Verberne, Riemer H. J. A. Slart, Oliver Lindner, Christopher Marcus Hacker

Risultato della ricerca: Contributo in rivistaArticolo in rivista

43 Citazioni (Scopus)

Abstract

The trade-off between resolution and count sensitivity dominates the performance of standard gamma cameras and dictates the need for relatively high doses of radioactivity of the used radiopharmaceuticals in order to limit image acquisition duration. The introduction of cadmium-zinc-telluride (CZT)-based cameras may overcome some of the limitations against conventional gamma cameras. CZT cameras used for the evaluation of myocardial perfusion have been shown to have a higher count sensitivity compared to conventional single photon emission computed tomography (SPECT) techniques. CZT image quality is further improved by the development of a dedicated three-dimensional iterative reconstruction algorithm, based on maximum likelihood expectation maximization (MLEM), which corrects for the loss in spatial resolution due to line response function of the collimator. All these innovations significantly reduce imaging time and result in a lower patient’s radiation exposure compared with standard SPECT. To guide current and possible future users of the CZT technique for myocardial perfusion imaging, the Cardiovascular Committee of the European Association of Nuclear Medicine, starting from the experience of its members, has decided to examine the current literature regarding procedures and clinical data on CZT cameras. The committee hereby aims 1) to identify the main acquisitions protocols; 2) to evaluate the diagnostic and prognostic value of CZT derived myocardial perfusion, and finally 3) to determine the impact of CZT on radiation exposure.
Lingua originaleEnglish
pagine (da-a)2423-2432
Numero di pagine10
RivistaEuropean Journal of Nuclear Medicine and Molecular Imaging
Volume43
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • CZT camera
  • Cadmium Compounds
  • Cardiac Imaging Techniques
  • Coronary Artery Disease
  • Coronary artery disease
  • Diagnosis
  • Equipment Design
  • Equipment Failure Analysis
  • Europe
  • Evidence-Based Medicine
  • Gamma Rays
  • Humans
  • Perfusion
  • Prognosis
  • Radiation Dosage
  • Radiation Exposure
  • Radionuclide Imaging
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tellurium
  • Zinc

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