Patterns of radiotherapy practice for pancreatic cancer: Results of the Gastrointestinal Radiation Oncology Study Group multi-institutional survey

Gian Carlo Mattiucci, Vincenzo Valentini, Gabriella Macchia, Luciana Caravatta, Vincenzo Fusco, Alessio Giuseppe Morganti, Aldo Sainato, Renato Talamini, Giovanni Boz, Almalina Bacigalupo, Michele Fiore, Maria Luisa Friso, Marco Lupattelli, Giovanna Mantello, Najla Slim, Piera Sciacero, Lucia Turri, Domenico Genovesi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

2 Citazioni (Scopus)

Abstract

No information is currently available regarding pancreatic cancer (PC) pattern of care in Italy. In the present study, a nationwide survey using a questionnaire was performed to enquire the local standards for PC diagnosis and radiotherapy treatment. Fifty-seven percent of 140 Italian centres completed questionnaire. The main causes of no radiotherapy indication were poor general condition (45%) and lack of guidelines (25%). Physicians (38%) employed neoadjuvant therapy in locally advanced PC patients, while in other centres (62%) adjuvant chemoradiation was administered. Adjuvant gemcitabine-based chemotherapy was selected as the treatment of choice by 59% of centres. Patients were treated mostly with doses of 50-54.9 Gy on the tumour (or bed) plus lymph nodes. A 3D-CRT technique was used in 81.2% of centres, while IMRT and IGRT were available in 61.2 and 48.7% of cases, respectively. Extensive variation exists with regard to patterns of care for PC in Italy. Nevertheless, cooperative studies emerging from this survey appeared beneficial.
Lingua originaleEnglish
pagine (da-a)382-390
Numero di pagine9
RivistaOncology Reports
Volume34
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • pancreatic cancer
  • radiotherapy

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