Pathologic changes after photodynamic therapy for Basal cell carcinoma and Bowen disease: a histologic and immunohistochemical investigation

F Fantini; A Greco; Am Cesinaro; T Surrenti; Ketty Peris; C Vaschieri; A Marconi; A Giannetti; C. Pincelli

doi:10.1001/archdermatol.2007.31

Pathologic changes after photodynamic therapy for Basal cell carcinoma and Bowen disease: a histologic and immunohistochemical investigation

F Fantini
, A Greco
, Am Cesinaro
, T Surrenti
, Ketty Peris
, C Vaschieri
, A Marconi
, A Giannetti
, C. Pincelli

Risultato della ricerca: Contributo in rivista › Articolo

26 Citazioni (Scopus)

Abstract

To investigate the in vivo reactions and the mechanisms of cell death after photodynamic therapy (PDT) for cutaneous carcinomas. Photodynamic therapy is a new treatment modality for nonmelanoma skin cancers. Its effects on target tissue have been well investigated in vitro, where apoptosis appears to be the main effector mechanism, but its effects remain undefined in vivo.

Lingua originale	Inglese
pagine (da-a)	186-194
Numero di pagine	9
Rivista	Archives of Dermatology
Volume	144
DOI	https://doi.org/10.1001/archdermatol.2007.31
Stato di pubblicazione	Pubblicato - 2008

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Keywords

Aged
Aged, 80 and over
Aminolevulinic Acid
Apoptosis
Biopsy
Bowen's Disease
Carcinoma, Basal Cell
Caspase 3
Enzyme Activation
Female
Humans
Immunohistochemistry
In Situ Nick-End Labeling
Male
Microscopy, Electron
Middle Aged
Photochemotherapy
Photosensitizing Agents
Proto-Oncogene Proteins c-bcl-2
Skin Neoplasms

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10.1001/archdermatol.2007.31

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title = "Pathologic changes after photodynamic therapy for Basal cell carcinoma and Bowen disease: a histologic and immunohistochemical investigation",

abstract = "To investigate the in vivo reactions and the mechanisms of cell death after photodynamic therapy (PDT) for cutaneous carcinomas. Photodynamic therapy is a new treatment modality for nonmelanoma skin cancers. Its effects on target tissue have been well investigated in vitro, where apoptosis appears to be the main effector mechanism, but its effects remain undefined in vivo.",

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author = "F Fantini and A Greco and Am Cesinaro and T Surrenti and Ketty Peris and C Vaschieri and A Marconi and A Giannetti and C. Pincelli",

year = "2008",

doi = "10.1001/archdermatol.2007.31",

language = "English",

volume = "144",

pages = "186--194",

journal = "Archives of Dermatology",

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publisher = "American Medical Association",

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T1 - Pathologic changes after photodynamic therapy for Basal cell carcinoma and Bowen disease: a histologic and immunohistochemical investigation

AU - Fantini, F

AU - Greco, A

AU - Cesinaro, Am

AU - Surrenti, T

AU - Peris, Ketty

AU - Vaschieri, C

AU - Marconi, A

AU - Giannetti, A

AU - Pincelli, C.

PY - 2008

Y1 - 2008

N2 - To investigate the in vivo reactions and the mechanisms of cell death after photodynamic therapy (PDT) for cutaneous carcinomas. Photodynamic therapy is a new treatment modality for nonmelanoma skin cancers. Its effects on target tissue have been well investigated in vitro, where apoptosis appears to be the main effector mechanism, but its effects remain undefined in vivo.

AB - To investigate the in vivo reactions and the mechanisms of cell death after photodynamic therapy (PDT) for cutaneous carcinomas. Photodynamic therapy is a new treatment modality for nonmelanoma skin cancers. Its effects on target tissue have been well investigated in vitro, where apoptosis appears to be the main effector mechanism, but its effects remain undefined in vivo.

KW - Aged

KW - Aged, 80 and over

KW - Aminolevulinic Acid

KW - Apoptosis

KW - Biopsy

KW - Bowen's Disease

KW - Carcinoma, Basal Cell

KW - Caspase 3

KW - Enzyme Activation

KW - Female

KW - Humans

KW - Immunohistochemistry

KW - In Situ Nick-End Labeling

KW - Male

KW - Microscopy, Electron

KW - Middle Aged

KW - Photochemotherapy

KW - Photosensitizing Agents

KW - Proto-Oncogene Proteins c-bcl-2

KW - Skin Neoplasms

KW - Aged

KW - Aged, 80 and over

KW - Aminolevulinic Acid

KW - Apoptosis

KW - Biopsy

KW - Bowen's Disease

KW - Carcinoma, Basal Cell

KW - Caspase 3

KW - Enzyme Activation

KW - Female

KW - Humans

KW - Immunohistochemistry

KW - In Situ Nick-End Labeling

KW - Male

KW - Microscopy, Electron

KW - Middle Aged

KW - Photochemotherapy

KW - Photosensitizing Agents

KW - Proto-Oncogene Proteins c-bcl-2

KW - Skin Neoplasms

UR - http://hdl.handle.net/10807/57531

U2 - 10.1001/archdermatol.2007.31

DO - 10.1001/archdermatol.2007.31

M3 - Article

SN - 0003-987X

VL - 144

SP - 186

EP - 194

JO - Archives of Dermatology

JF - Archives of Dermatology

ER -

Pathologic changes after photodynamic therapy for Basal cell carcinoma and Bowen disease: a histologic and immunohistochemical investigation

Abstract

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Keywords

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