Pathologic changes after photodynamic therapy for Basal cell carcinoma and Bowen disease: a histologic and immunohistochemical investigation

Ketty Peris, F Fantini, A Greco, Am Cesinaro, T Surrenti, C Vaschieri, A Marconi, A Giannetti, C. Pincelli

Risultato della ricerca: Contributo in rivistaArticolo in rivista

26 Citazioni (Scopus)

Abstract

To investigate the in vivo reactions and the mechanisms of cell death after photodynamic therapy (PDT) for cutaneous carcinomas. Photodynamic therapy is a new treatment modality for nonmelanoma skin cancers. Its effects on target tissue have been well investigated in vitro, where apoptosis appears to be the main effector mechanism, but its effects remain undefined in vivo.
Lingua originaleEnglish
pagine (da-a)186-194
Numero di pagine9
RivistaArchives of Dermatology
Volume144
DOI
Stato di pubblicazionePubblicato - 2008

Keywords

  • Aged
  • Aged, 80 and over
  • Aminolevulinic Acid
  • Apoptosis
  • Biopsy
  • Bowen's Disease
  • Carcinoma, Basal Cell
  • Caspase 3
  • Enzyme Activation
  • Female
  • Humans
  • Immunohistochemistry
  • In Situ Nick-End Labeling
  • Male
  • Microscopy, Electron
  • Middle Aged
  • Photochemotherapy
  • Photosensitizing Agents
  • Proto-Oncogene Proteins c-bcl-2
  • Skin Neoplasms

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