Pathogenesis of nephrolithiasis: recent insight from cell biology and renal pathology

Giovanni Gambaro, Antonia Fabris, Cataldo Abaterusso, Alex Cosaro, Monica Ceol, Federica Mezzabotta, Rossella Torregrossa, Emilia Tiralongo, Dorella Del Prete, Angela D'Angelo, Franca Anglani

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

4 Citazioni (Scopus)

Abstract

Randall's plaques are very common in idiopathic calcium-oxalate nephrolithiasis. These papillary plaques have an apatite mineral structure. While these calcium deposits are generally assumed to be secondary to a purely physico-chemical phenomenon, we advance the hypothesis that they form due to a truly ectopic biomineralization in the renal tissue, and that Henle's loop epithelial cells, or pericyte-like interstitial cells, or papillary stem cells differentiating along a bone lineage might be involved.
Lingua originaleEnglish
pagine (da-a)107-109
Numero di pagine3
RivistaClinical Cases in Mineral and Bone Metabolism
Volume5
Stato di pubblicazionePubblicato - 2008

Keywords

  • Nephrolithiasis

Fingerprint Entra nei temi di ricerca di 'Pathogenesis of nephrolithiasis: recent insight from cell biology and renal pathology'. Insieme formano una fingerprint unica.

Cita questo