Palladium-Catalyzed C12-Selective Direct Arylation of [1,2- c ]Quinazolin-6(5 H)-ones

Antonio Arcadi; Sandro Cacchi; Giancarlo Fabrizi; Andrea Fochetti; Francesca Ghirga; Antonella Goggiamani; Antonia Iazzetti; Fabio Marinelli

doi:10.1055/s-0037-1610711

Palladium-Catalyzed C12-Selective Direct Arylation of [1,2- c ]Quinazolin-6(5 H)-ones

Antonio Arcadi
, Sandro Cacchi
, Giancarlo Fabrizi
, Andrea Fochetti
, Francesca Ghirga
, Antonella Goggiamani^*
, Antonia Iazzetti^*
, Fabio Marinelli

^*Autore corrispondente per questo lavoro

University of L'Aquila
University of Rome La Sapienza
Italian Institute of Technology

Risultato della ricerca: Contributo in rivista › Articolo

Abstract

A straightforward approach to the synthesis of the challenging 12-arylindolo[1,2- c ]quinazolin-6(5 H)-ones through the palladium-catalyzed direct arylation of N -benzyl and NH-free [1,2- c ]quinazolin-6(5 H)-ones with aryl halides is described.

Lingua originale	Inglese
pagine (da-a)	3287-3294
Numero di pagine	8
Rivista	Synthesis
Volume	51
DOI	https://doi.org/10.1055/s-0037-1610711
Stato di pubblicazione	Pubblicato - 2019

Keywords

arylation
indoles
palladium
polycycles
quinazolinones

Accesso al documento

10.1055/s-0037-1610711

Altri file e collegamenti

Link a IRIS PubliCatt

Cita questo

@article{27cf2ddb216b4ac9bec23f7611640706,

title = "Palladium-Catalyzed C12-Selective Direct Arylation of [1,2- c ]Quinazolin-6(5 H)-ones",

abstract = "A straightforward approach to the synthesis of the challenging 12-arylindolo[1,2- c ]quinazolin-6(5 H)-ones through the palladium-catalyzed direct arylation of N -benzyl and NH-free [1,2- c ]quinazolin-6(5 H)-ones with aryl halides is described.",

keywords = "arylation, indoles, palladium, polycycles, quinazolinones, arylation, indoles, palladium, polycycles, quinazolinones",

author = "Antonio Arcadi and Sandro Cacchi and Giancarlo Fabrizi and Andrea Fochetti and Francesca Ghirga and Antonella Goggiamani and Antonia Iazzetti and Fabio Marinelli",

year = "2019",

doi = "10.1055/s-0037-1610711",

language = "English",

volume = "51",

pages = "3287--3294",

journal = "Synthesis",

issn = "0039-7881",

publisher = "Georg Thieme Verlag",

}

TY - JOUR

T1 - Palladium-Catalyzed C12-Selective Direct Arylation of [1,2- c ]Quinazolin-6(5 H)-ones

AU - Arcadi, Antonio

AU - Cacchi, Sandro

AU - Fabrizi, Giancarlo

AU - Fochetti, Andrea

AU - Ghirga, Francesca

AU - Goggiamani, Antonella

AU - Iazzetti, Antonia

AU - Marinelli, Fabio

PY - 2019

Y1 - 2019

N2 - A straightforward approach to the synthesis of the challenging 12-arylindolo[1,2- c ]quinazolin-6(5 H)-ones through the palladium-catalyzed direct arylation of N -benzyl and NH-free [1,2- c ]quinazolin-6(5 H)-ones with aryl halides is described.

AB - A straightforward approach to the synthesis of the challenging 12-arylindolo[1,2- c ]quinazolin-6(5 H)-ones through the palladium-catalyzed direct arylation of N -benzyl and NH-free [1,2- c ]quinazolin-6(5 H)-ones with aryl halides is described.

KW - arylation

KW - indoles

KW - palladium

KW - polycycles

KW - quinazolinones

KW - arylation

KW - indoles

KW - palladium

KW - polycycles

KW - quinazolinones

UR - http://hdl.handle.net/10807/198663

U2 - 10.1055/s-0037-1610711

DO - 10.1055/s-0037-1610711

M3 - Article

SN - 0039-7881

VL - 51

SP - 3287

EP - 3294

JO - Synthesis

JF - Synthesis

ER -

Palladium-Catalyzed C12-Selective Direct Arylation of [1,2- c ]Quinazolin-6(5 H)-ones

Abstract

Keywords

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo