TY - JOUR
T1 - Pain Management through Neurocognitive Therapeutic Exercises in Hypermobile Ehlers-Danlos Syndrome Patients with Chronic Low Back Pain
AU - Celletti, Claudia
AU - Paolucci, Teresa
AU - Maggi, Loredana
AU - Volpi, Giordana
AU - Billi, Mariangela
AU - Mollica, Roberta
AU - Camerota, Filippo
PY - 2021
Y1 - 2021
N2 - Background. The hypermobile type of Ehlers-Danlos syndrome (hEDS) is likely the most common hereditary disorder of connective tissue mainly characterized by joint hypermobility. Patients with hEDS suffer joint pain, in particular low back pain, commonly resistant to drug therapy. The aim of this research was to evaluate a neurocognitive rehabilitation approach based not only on the motion and function recovery but also on the pain management. Methods. In this nonrandomized clinical trial, eighteen hEDS patients (4 males and 14 females) with mean age 21 years (range 13-55) were recruited and evaluated before and after three months of rehabilitation treatment. Results. The outcome scores showed significant statistical results after treatment in reducing pain symptoms (numerical rating scale, P=0.003; McGill (total score), P=0.03), fatigue (fatigue severity scale, P=0.03), fear of movement (Tampa scale, P=0.003), and pain-associated disability (Oswestry disability index, P=0.03). Conclusion. The clinical results observed in our study seem to confirm the role of a specific neurocognitive rehabilitation program in the chronic pain management in the Ehlers-Danlos syndrome; the rehabilitation treatment should be tailored on patient problems and focused not only in the recovery of movement but also on pain perception.
AB - Background. The hypermobile type of Ehlers-Danlos syndrome (hEDS) is likely the most common hereditary disorder of connective tissue mainly characterized by joint hypermobility. Patients with hEDS suffer joint pain, in particular low back pain, commonly resistant to drug therapy. The aim of this research was to evaluate a neurocognitive rehabilitation approach based not only on the motion and function recovery but also on the pain management. Methods. In this nonrandomized clinical trial, eighteen hEDS patients (4 males and 14 females) with mean age 21 years (range 13-55) were recruited and evaluated before and after three months of rehabilitation treatment. Results. The outcome scores showed significant statistical results after treatment in reducing pain symptoms (numerical rating scale, P=0.003; McGill (total score), P=0.03), fatigue (fatigue severity scale, P=0.03), fear of movement (Tampa scale, P=0.003), and pain-associated disability (Oswestry disability index, P=0.03). Conclusion. The clinical results observed in our study seem to confirm the role of a specific neurocognitive rehabilitation program in the chronic pain management in the Ehlers-Danlos syndrome; the rehabilitation treatment should be tailored on patient problems and focused not only in the recovery of movement but also on pain perception.
KW - Chronic Pain/ rehabilitation
KW - Chronic Pain/ rehabilitation
UR - http://hdl.handle.net/10807/304121
U2 - 10.1155/2021/6664864
DO - 10.1155/2021/6664864
M3 - Article
SN - 2314-6141
VL - 1
SP - N/A-N/A
JO - BioMed Research International
JF - BioMed Research International
ER -