Overview of Management of Myocardial Ischemia: a Mechanistic-Based Approach

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4 Citazioni (Scopus)

Abstract

Pharmacologic treatment of myocardial ischemia in patients with chronic stable angina (CSA) is mainly based on heart rate lowering drugs and vasodilator agents. Other drugs are available, however, that act by some peculiar mechanism (ranolazine, trimetazidine) and may add potential anti-ischemic and anti-anginal effects to standard therapeutic mechanisms. While anti-ischemic agents are crucial for controlling angina symptoms and improving quality of life, whether myocardial ischemia portends an ominous prognosis and its suppression improves clinical outcome in CSA patients remain debated issues.
Lingua originaleEnglish
pagine (da-a)341-349
Numero di pagine9
RivistaCardiovascular Drugs and Therapy
Volume30
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • Angina
  • Cardiology and Cardiovascular Medicine
  • Cardiovascular Agents
  • Clinical outcome
  • Heart Rate
  • Humans
  • Medical therapy
  • Myocardial Ischemia
  • Myocardial ischemia
  • Pathophysiologic mechanisms
  • Pharmacology
  • Pharmacology (medical)

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