Overexpression of Enterococcus faecalis elr operon protects from phagocytosis

Francesca Bugli; Maurizio Sanguinetti; Brunella Posteraro; Naima G. Cortes-Perez; Romain Dumoulin; Stéphane Gaubert; Caroline Lacoux; Rebeca Martin; Sophie Chat; Kevin Piquand; Thierry Meylheuc; Philippe Langella; Lionel Rigottier-Gois; Pascale Serror

doi:10.1186/s12866-015-0448-y

Overexpression of Enterococcus faecalis elr operon protects from phagocytosis

Francesca Bugli, Maurizio Sanguinetti, Brunella Posteraro, Naima G. Cortes-Perez, Romain Dumoulin, Stéphane Gaubert, Caroline Lacoux, Rebeca Martin, Sophie Chat, Kevin Piquand, Thierry Meylheuc, Philippe Langella, Lionel Rigottier-Gois, Pascale Serror

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

7 Citazioni (Scopus)

Abstract

Mechanisms underlying the transition from commensalism to virulence in Enterococcus faecalis are not fully understood. We previously identified the enterococcal leucine-rich protein A (ElrA) as a virulence factor of E. faecalis. The elrA gene is part of an operon that comprises four other ORFs encoding putative surface proteins of unknown function.

Lingua originale	English
pagine (da-a)	112-117
Numero di pagine	6
Rivista	BMC Microbiology
Volume	15
DOI	https://doi.org/10.1186/s12866-015-0448-y
Stato di pubblicazione	Pubblicato - 2015

Keywords

Enterococcus

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10.1186/s12866-015-0448-y

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Bugli, Francesca ; Sanguinetti, Maurizio ; Posteraro, Brunella ; Cortes-Perez, Naima G. ; Dumoulin, Romain ; Gaubert, Stéphane ; Lacoux, Caroline ; Martin, Rebeca ; Chat, Sophie ; Piquand, Kevin ; Meylheuc, Thierry ; Langella, Philippe ; Rigottier-Gois, Lionel ; Serror, Pascale. / Overexpression of Enterococcus faecalis elr operon protects from phagocytosis. In: BMC Microbiology. 2015 ; Vol. 15. pagg. 112-117.

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title = "Overexpression of Enterococcus faecalis elr operon protects from phagocytosis",

abstract = "Mechanisms underlying the transition from commensalism to virulence in Enterococcus faecalis are not fully understood. We previously identified the enterococcal leucine-rich protein A (ElrA) as a virulence factor of E. faecalis. The elrA gene is part of an operon that comprises four other ORFs encoding putative surface proteins of unknown function.",

keywords = "Enterococcus, Enterococcus",

author = "Francesca Bugli and Maurizio Sanguinetti and Brunella Posteraro and Cortes-Perez, {Naima G.} and Romain Dumoulin and St{\'e}phane Gaubert and Caroline Lacoux and Rebeca Martin and Sophie Chat and Kevin Piquand and Thierry Meylheuc and Philippe Langella and Lionel Rigottier-Gois and Pascale Serror",

year = "2015",

doi = "10.1186/s12866-015-0448-y",

language = "English",

volume = "15",

pages = "112--117",

journal = "BMC Microbiology",

issn = "1471-2180",

publisher = "BIOMED CENTRAL LTD, MIDDLESEX HOUSE, 34-42 CLEVELAND ST, LONDON, ENGLAND, W1T 4LB",

}

Overexpression of Enterococcus faecalis elr operon protects from phagocytosis. / Bugli, Francesca ; Sanguinetti, Maurizio ; Posteraro, Brunella; Cortes-Perez, Naima G.; Dumoulin, Romain; Gaubert, Stéphane; Lacoux, Caroline; Martin, Rebeca; Chat, Sophie; Piquand, Kevin; Meylheuc, Thierry; Langella, Philippe; Rigottier-Gois, Lionel; Serror, Pascale.

In: BMC Microbiology, Vol. 15, 2015, pag. 112-117.

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

TY - JOUR

T1 - Overexpression of Enterococcus faecalis elr operon protects from phagocytosis

AU - Bugli, Francesca

AU - Sanguinetti, Maurizio

AU - Posteraro, Brunella

AU - Cortes-Perez, Naima G.

AU - Dumoulin, Romain

AU - Gaubert, Stéphane

AU - Lacoux, Caroline

AU - Martin, Rebeca

AU - Chat, Sophie

AU - Piquand, Kevin

AU - Meylheuc, Thierry

AU - Langella, Philippe

AU - Rigottier-Gois, Lionel

AU - Serror, Pascale

PY - 2015

Y1 - 2015

N2 - Mechanisms underlying the transition from commensalism to virulence in Enterococcus faecalis are not fully understood. We previously identified the enterococcal leucine-rich protein A (ElrA) as a virulence factor of E. faecalis. The elrA gene is part of an operon that comprises four other ORFs encoding putative surface proteins of unknown function.

AB - Mechanisms underlying the transition from commensalism to virulence in Enterococcus faecalis are not fully understood. We previously identified the enterococcal leucine-rich protein A (ElrA) as a virulence factor of E. faecalis. The elrA gene is part of an operon that comprises four other ORFs encoding putative surface proteins of unknown function.

KW - Enterococcus

UR - http://hdl.handle.net/10807/69049

U2 - 10.1186/s12866-015-0448-y

DO - 10.1186/s12866-015-0448-y

M3 - Article

VL - 15

SP - 112

EP - 117

JO - BMC Microbiology

JF - BMC Microbiology

SN - 1471-2180

ER -

Overexpression of Enterococcus faecalis elr operon protects from phagocytosis

Abstract

Keywords

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