Overall exposure of european adult population to mycotoxins by statistically modelled biomonitoring data

Paola Battilani, Barbara De Santis, Francesca Debegnach, Piero Toscano, Alfonso Crisci, Carlo Brera

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

This study presents the exposure scenario to mycotoxins of adult population throughout Europe. The urinary biomarkers values were obtained by modelling data from two European projects. Exposure to AFB1, OTA, CIT, FBs, DON, NIV and T2/HT2 are presented. The main output obtained refers to a concern for public health about AFM1, FBs, T2/HT2 and NIV, and low concern for OTA, DON and CIT. The margin of exposure for AFM1 did not respect the reference value of 10,000 considered of low priority for risk; for Fusarium toxins, FBs and T2/HT2, probable daily intake (PDI) values resulted about ten times higher than their tolerable daily intake and NIV presented the most critical situation with a calculated PDI 30 times higher than the reference TDI value. North and South Europe scenarios were also depicted by clustering biomonitoring data. OTA and DON showed to be prevalent in Northern countries and the opposite was noticed for ZEN, higher in Southern countries. The critical issues of the availability of records feeding the dataset and of the accuracy of excretion rate for some mycotoxins are source of uncertainty for the reliability of the outputs, nevertheless the time is ripe for asking for more concrete HBM values and/or HBM-HBGV which would help in interpreting the burden of mycotoxins in Europe.
Lingua originaleEnglish
pagine (da-a)1-17
Numero di pagine17
RivistaToxins
Volume13
DOI
Stato di pubblicazionePubblicato - 2021

Keywords

  • Biomarker
  • Biomonitoring
  • Exposure assessment
  • Mycotoxin
  • Provisional daily intake

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