Osteoradionecrosis of the jaws due to teeth extractions during and after radiotherapy: A systematic review

Carlo Lajolo, Cosimo Rupe, Gioele Gioco, Giuseppe Troiano, Romeo Patini, Massimo Petruzzi, Francesco Micciche', Michele Giuliani

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Teeth extractions before or after radiotherapy (RT) could be procedures at high risk for osteoradionecrosis (ORN) onset. This systematic review was performed to investigate the ORN incidence following teeth extractions during and after RT for head and neck (H&N) cancer and to evaluate any other possible risk factor. Methods: This systematic review was conducted according to PRISMA protocol, and the PROSPERO registration number was CRD42018079986. An electronic search was performed on the following search engines: PubMed, Scopus, and Web of Science. A cumulative meta‐analysis was performed. Results: Two thousand two hundred and eighty‐one records were screened, and nine were finally included. This systematic review revealed an ORN incidence of 5.8% (41 patients out of 462, 95% CI = 2.3–9.4); 3 ORN developed in the maxilla. No other clinical risk factors were detected. Conclusion: Post‐RT teeth extractions represent a major risk factor for ORN development, especially in the mandible, with a diminishing trend in the last years. Further research on other possible risk factors might improve this evidence.
Lingua originaleEnglish
pagine (da-a)5798-5798
Numero di pagine1
RivistaCancers
Volume13
DOI
Stato di pubblicazionePubblicato - 2021

Keywords

  • Head and neck cancer
  • Jaw
  • Radiotherapy
  • Tooth extraction
  • osteoradionecrosis

Fingerprint

Entra nei temi di ricerca di 'Osteoradionecrosis of the jaws due to teeth extractions during and after radiotherapy: A systematic review'. Insieme formano una fingerprint unica.

Cita questo