Oropharyngoesophageal scintigraphy in the diagnostic algorithm of laryngopharyngeal reflux disease: A useful exam?

Jacopo Galli, Mariangela Volante, Claudio Parrilla, Mario Rigante, Venanzio Valenza

Risultato della ricerca: Contributo in rivistaArticolo in rivista


OBJECTIVE: To evaluate the role of oropharyngoesophageal scintigraphy in the diagnostic approach to patients with laryngopharyngeal reflux (LPR). STUDY DESIGN: Forty-one patients with chronic laryngopharyngeal symptoms and a control group of 15 healthy volunteers were examined. All subjects underwent standard oropharyngoesophageal scintigraphy. The following parameters were considered: activity-time curves, presence of double peaks and reduced slope in oropharyngeal phase, presence of accelerated or slowed esophagogastric transit, persistence of radioactive material on the pharyngeal or esophageal mucosa, and presence of gastroesophageal reflux (GER) under exercise. RESULTS: There were objective signs of laryngeal reflux in 80.5% of the patients. In 82.9%, scintigraphy documented several associated morphofunctional pathologic patterns: positive GER test (61.0%), presence of double peaks (36.6%), indirect signs of pharyngoesophageal inflammation (31.7%), hypotonic lower esophageal sphincter (17.1%), and slowed esophageal clearance (9.8%). CONCLUSIONS: Oropharyngoesophageal scintigraphy may be used as preliminary examination in outpatients with signs and symptoms of LPR. Cases of classic gastroesophageal reflux disease could be separated from those of LPR disease and therefore submitted to more invasive instrumental examinations. Copyright © 2005 by the American Academy of Otolaryngology-Head and Neck Surgery Foundation, Inc.
Lingua originaleEnglish
pagine (da-a)717-721
Numero di pagine5
Stato di pubblicazionePubblicato - 2005


  • Adult
  • Aged
  • Algorithms
  • Female
  • Gastroesophageal Reflux
  • Humans
  • Hypopharynx
  • Laryngeal Diseases
  • Male
  • Middle Aged
  • Pharyngeal Diseases
  • Radiation Dosage
  • Radionuclide Imaging


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