Orbito-Frontal Cortex Hypometabolism in Children With Post-COVID Condition (Long COVID): A Preliminary Experience

Fabrizio Cocciolillo; Daniela Di Giuda; Rosa Morello; Cristina De Rose; Piero Valentini; Danilo Buonsenso

doi:10.1097/INF.0000000000003578

Orbito-Frontal Cortex Hypometabolism in Children With Post-COVID Condition (Long COVID): A Preliminary Experience

Fabrizio Cocciolillo
, Daniela Di Giuda
, Rosa Morello
, Cristina De Rose
, Piero Valentini
, Danilo Buonsenso^*

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo › peer review

Abstract

We describe 3 children with new-onset neurocognitive problems after coronavirus disease 2019 (COVID-19), that showed, at the brain [18F]-fluorodeoxyglucose positron emission tomography/computed tomography, hypometabolism in the left orbito-frontal region. The voxel-wise analysis confirmed a cluster of hypometabolic voxels in this region with a peak at -18/46/-4mm (179 voxels, T-Score 8.1). These findings may explain neurocognitive symptoms that some children develop after COVID-19 and require further investigations

Lingua originale	Inglese
pagine (da-a)	663-665
Numero di pagine	3
Rivista	THE PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume	41
DOI	https://doi.org/10.1097/INF.0000000000003578
Stato di pubblicazione	Pubblicato - 2022

Keywords

PET
brain
children
long covid
orbito-frontal cortex

Accesso al documento

10.1097/INF.0000000000003578

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title = "Orbito-Frontal Cortex Hypometabolism in Children With Post-COVID Condition (Long COVID): A Preliminary Experience",

abstract = "We describe 3 children with new-onset neurocognitive problems after coronavirus disease 2019 (COVID-19), that showed, at the brain [18F]-fluorodeoxyglucose positron emission tomography/computed tomography, hypometabolism in the left orbito-frontal region. The voxel-wise analysis confirmed a cluster of hypometabolic voxels in this region with a peak at -18/46/-4mm (179 voxels, T-Score 8.1). These findings may explain neurocognitive symptoms that some children develop after COVID-19 and require further investigations",

keywords = "PET, brain, children, long covid, orbito-frontal cortex, PET, brain, children, long covid, orbito-frontal cortex",

author = "Fabrizio Cocciolillo and \{Di Giuda\}, Daniela and Rosa Morello and \{De Rose\}, Cristina and Piero Valentini and Danilo Buonsenso",

year = "2022",

doi = "10.1097/INF.0000000000003578",

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journal = "THE PEDIATRIC INFECTIOUS DISEASE JOURNAL",

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publisher = "Lippincott, Williams \& Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: [email protected], INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320",

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AU - Cocciolillo, Fabrizio

AU - Di Giuda, Daniela

AU - Morello, Rosa

AU - De Rose, Cristina

AU - Valentini, Piero

AU - Buonsenso, Danilo

PY - 2022

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N2 - We describe 3 children with new-onset neurocognitive problems after coronavirus disease 2019 (COVID-19), that showed, at the brain [18F]-fluorodeoxyglucose positron emission tomography/computed tomography, hypometabolism in the left orbito-frontal region. The voxel-wise analysis confirmed a cluster of hypometabolic voxels in this region with a peak at -18/46/-4mm (179 voxels, T-Score 8.1). These findings may explain neurocognitive symptoms that some children develop after COVID-19 and require further investigations

AB - We describe 3 children with new-onset neurocognitive problems after coronavirus disease 2019 (COVID-19), that showed, at the brain [18F]-fluorodeoxyglucose positron emission tomography/computed tomography, hypometabolism in the left orbito-frontal region. The voxel-wise analysis confirmed a cluster of hypometabolic voxels in this region with a peak at -18/46/-4mm (179 voxels, T-Score 8.1). These findings may explain neurocognitive symptoms that some children develop after COVID-19 and require further investigations

KW - PET

KW - brain

KW - children

KW - long covid

KW - orbito-frontal cortex

KW - PET

KW - brain

KW - children

KW - long covid

KW - orbito-frontal cortex

UR - http://hdl.handle.net/10807/280996

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M3 - Article

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JO - THE PEDIATRIC INFECTIOUS DISEASE JOURNAL

JF - THE PEDIATRIC INFECTIOUS DISEASE JOURNAL

ER -

Orbito-Frontal Cortex Hypometabolism in Children With Post-COVID Condition (Long COVID): A Preliminary Experience

Abstract

Keywords

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