Optical platelet aggregation versus thromboxane metabolites in healthy individuals and patients with stable coronary artery disease after low-dose aspirin administration

Bianca Rocca, Ss Hedegaard, A Hvas, E Groove, J Refìsgaard, G Davi, S Kristensen

Risultato della ricerca: Contributo in rivistaArticolo in rivista

36 Citazioni (Scopus)

Abstract

Aspirin reduces cardiovascular events in patients with coronary artery disease (CAD), but studies report a highly variable response to aspirin, often referred to as 'aspirin low-responsiveness'. We investigated whether 75 mg of daily non-enteric coated aspirin would completely inhibit the platelet cyclooxygenase-1 activity to a comparable extent in healthy individuals and stable CAD patients.
Lingua originaleEnglish
pagine (da-a)96-100
Numero di pagine5
RivistaThrombosis Research
Volume124
DOI
Stato di pubblicazionePubblicato - 2009

Keywords

  • Adult
  • Aged
  • Aspirin
  • Blood Platelets
  • Coronary Artery Disease
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Male
  • Middle Aged
  • Patient Compliance
  • Platelet Aggregation
  • Platelet Aggregation Inhibitors
  • Tablets, Enteric-Coated
  • Thromboxanes
  • Time Factors

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