Optical and Mechanical Investigations of Nanostructures for Biomolecular Detection

Gabriele Ferrini, Francesco Banfi, Claudio Giannetti, Giovanna Malegori, Damiano Nardi

Risultato della ricerca: Contributo in libroChapter

4 Citazioni (Scopus)

Abstract

Since Luigi Galvani (1737–1798) began his studies, physics and biology have inter- acted and many tools from physics have been used in the biological sciences. Today the availability of new microscopic techniques has pushed the boundaries from the μm to the (sub-) nm level. These possibilities stimulate to find ever more creative ways of using physics, material science, and biology combined together. In particular, the development of techniques capable of measuring the chemical and mechanical state of biological samples, in vivo and with attention to molecular dynamics localized at surfaces is of great interest. An approach trying to combine these aspects will be reviewed here, based on the following techniques: (a) Optical detection based on evanescent wave spectroscopy, (b) femtosecond laser pulses used to excite thermal and mechanical transients in na- noengineered materials, (c) Non-Contact Atomic Force Microscopy (NC-AFM) and force spectroscopy.
Lingua originaleEnglish
Titolo della pubblicazione ospiteNanomedicine and Cancer Therapies
EditorSebastian Mathew, Ninan Neethu, Elias Eldho
Pagine170-184
Numero di pagine15
Stato di pubblicazionePubblicato - 2012

Serie di pubblicazioni

NomeAdvances in Nanoscience and Nanotechnology

Keywords

  • atomic force microscopy
  • biomolecules
  • nanomedicine
  • nanostructures
  • optics

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