Onset of coeliac disease during treatment with interferon for chronic hepatitis C.

Giovanni Cammarota*, Lucio Cuoco, Rossella Cianci, Franco Pandolfi, Giovanni Battista Gasbarrini

*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivistaArticolo

Abstract

The immunomodulatory properties of interferon may concur to precipitate or worsen an underlying autoimmune disorders. We report the cases of two men who displayed the various features of coeliac disease during a treatment with 4-interferon (in one case associated with ribavirin) for chronic hepatitis C. The patients stopped the interferon treatment and the symptoms and histological disorders improved after a gluten-free diet. Alpha-interferon is available worldwide for treatment of chronic viral hepatitis. Before treatment with this drug, the patients would have to be monitored for coeliac disease.
Lingua originaleInglese
pagine (da-a)1494-1495
Numero di pagine1490
RivistaThe Lancet
Volume356
Numero di pubblicazione9240
DOI
Stato di pubblicazionePubblicato - 2000

All Science Journal Classification (ASJC) codes

  • Medicina Generale

Keywords

  • celiac disease
  • chronic Hepatitis

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