Onset of coeliac disease during treatment with interferon for chronic hepatitis C.

Giovanni Cammarota; Lucio Cuoco; Rossella Cianci; Franco Pandolfi; Giovanni Battista Gasbarrini

doi:10.1016/S0140-6736(00)02880-4

Onset of coeliac disease during treatment with interferon for chronic hepatitis C.

Giovanni Cammarota, Lucio Cuoco, Rossella Cianci, Franco Pandolfi, Giovanni Battista Gasbarrini

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Abstract

The immunomodulatory properties of interferon may concur to precipitate or worsen an underlying autoimmune disorders. We report the cases of two men who displayed the various features of coeliac disease during a treatment with 4-interferon (in one case associated with ribavirin) for chronic hepatitis C. The patients stopped the interferon treatment and the symptoms and histological disorders improved after a gluten-free diet. Alpha-interferon is available worldwide for treatment of chronic viral hepatitis. Before treatment with this drug, the patients would have to be monitored for coeliac disease.

Lingua originale	English
pagine (da-a)	1494-1495
Numero di pagine	1490
Rivista	The Lancet
Volume	356
DOI	https://doi.org/10.1016/S0140-6736(00)02880-4
Stato di pubblicazione	Pubblicato - 2000

Keywords

celiac disease
chronic Hepatitis

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10.1016/S0140-6736(00)02880-4

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abstract = "The immunomodulatory properties of interferon may concur to precipitate or worsen an underlying autoimmune disorders. We report the cases of two men who displayed the various features of coeliac disease during a treatment with 4-interferon (in one case associated with ribavirin) for chronic hepatitis C. The patients stopped the interferon treatment and the symptoms and histological disorders improved after a gluten-free diet. Alpha-interferon is available worldwide for treatment of chronic viral hepatitis. Before treatment with this drug, the patients would have to be monitored for coeliac disease.",

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author = "Giovanni Cammarota and Lucio Cuoco and Rossella Cianci and Franco Pandolfi and Gasbarrini, {Giovanni Battista}",

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AU - Cammarota, Giovanni

AU - Cuoco, Lucio

AU - Cianci, Rossella

AU - Pandolfi, Franco

AU - Gasbarrini, Giovanni Battista

PY - 2000

Y1 - 2000

N2 - The immunomodulatory properties of interferon may concur to precipitate or worsen an underlying autoimmune disorders. We report the cases of two men who displayed the various features of coeliac disease during a treatment with 4-interferon (in one case associated with ribavirin) for chronic hepatitis C. The patients stopped the interferon treatment and the symptoms and histological disorders improved after a gluten-free diet. Alpha-interferon is available worldwide for treatment of chronic viral hepatitis. Before treatment with this drug, the patients would have to be monitored for coeliac disease.

AB - The immunomodulatory properties of interferon may concur to precipitate or worsen an underlying autoimmune disorders. We report the cases of two men who displayed the various features of coeliac disease during a treatment with 4-interferon (in one case associated with ribavirin) for chronic hepatitis C. The patients stopped the interferon treatment and the symptoms and histological disorders improved after a gluten-free diet. Alpha-interferon is available worldwide for treatment of chronic viral hepatitis. Before treatment with this drug, the patients would have to be monitored for coeliac disease.

KW - celiac disease

KW - chronic Hepatitis

KW - celiac disease

KW - chronic Hepatitis

UR - http://hdl.handle.net/10807/187115

U2 - 10.1016/S0140-6736(00)02880-4

DO - 10.1016/S0140-6736(00)02880-4

M3 - Article

SN - 0140-6736

VL - 356

SP - 1494

EP - 1495

JO - The Lancet

JF - The Lancet

ER -

Onset of coeliac disease during treatment with interferon for chronic hepatitis C.

Abstract

Keywords

OSS delle Nazioni Unite

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