Ondansetron for food protein-induced enterocolitis syndrome

Stefano Miceli Sopo, Andrea Battista, Monica Greco, Serena Monaco

Risultato della ricerca: Contributo in rivistaArticolo in rivista

42 Citazioni (Scopus)


Recently, a study on 5 patients [Holbrook et al.: J Allergy Clin Immunol 2013;132:1219-1220] documented the efficacy of the intravenous administration of ondansetron in children with acute symptoms due to food protein-induced enterocolitis syndrome (FPIES). We report on the experience at our institution using ondansetron during oral food challenge (OFC) in 5 children affected by FPIES. In all 5 cases, the use of intramuscular ondansetron led to a complete and rapid resolution of symptoms within 15 min. Intramuscular administration, without the need for intravenous access for an infusion or steroid administration, enables this therapy to be easily performed, even at home (i.e. out of a hospital setting). A home treatment with ondansetron cannot be considered as an alternative to a medical examination with eventual treatment in hospital, which is advised after any acute episode of FPIES. We consider ondansetron to be very useful in the management of acute FPIES. Further study is required to confirm its efficacy. © 2014 S. Karger AG, Basel.
Lingua originaleEnglish
pagine (da-a)137-139
Numero di pagine3
RivistaInternational Archives of Allergy and Immunology
Stato di pubblicazionePubblicato - 2014


  • Food allergy
  • Food protein-induced enterocolitis
  • Ondansetron
  • Oral food challenge


Entra nei temi di ricerca di 'Ondansetron for food protein-induced enterocolitis syndrome'. Insieme formano una fingerprint unica.

Cita questo