TY - JOUR
T1 - Olfactory perception rehabilitation after total laryngectomy (OPRAT): proposal of a new protocol based on training of sensory perception skills
AU - Longobardi, Ylenia
AU - Parrilla, Claudio
AU - Di Cintio, Giovanni
AU - De Corso, Eugenio
AU - Marenda, Maria Elisabetta
AU - Mari, Giorgia
AU - Paludetti, Gaetano
AU - D'Alatri, Lucia
AU - Passali, Giulio Cesare
PY - 2020
Y1 - 2020
N2 - PURPOSE:
We aim to propose a new protocol for olfaction rehabilitation after total laryngectomy based on training of sensory perception levels using the Nasal Airflow-Inducing Maneuver.
METHODS:
This is a randomized clinical trial including patients undergoing total laryngectomy between March 2010 and March 2019. Patients with nasal or oral abnormalities, prior olfaction impairment, a muco-ciliary transport time higher than 30 min, positive history for feeding, and neurological disorders were excluded. Thirty-three patients were enrolled and were randomized into two groups: an Experimental group, submitted to the new protocol (olfactory perception rehabilitation after total laryngectomy-OPRAT) and a Control group that did not receive any treatment. Subjective Olfactometry, Chemosensory Complaints Score, and University of Washington Quality of Life version 4 questionnaires were used to assess the outcomes before and after treatment, and at 3-month, 6-month, and 10-month follow-up.
RESULTS:
Among the 33 patients included (32 men and 1 woman; mean age, 67.94 ± 5.64 years), 17 were subjected to olfaction rehabilitation and 16 did not receive any treatment. At baseline evaluation, there were not significant differences between the two groups. At the end of treatment, the rehabilitated group improved their olfaction capability significantly. Such improvement remained stable over time, and after 10 months, only the Experimental group had significant improvements in all outcome measures.
CONCLUSIONS:
The OPRAT may guarantee excellent results in the short- and long-term time with positive effects on the Quality of Life.
AB - PURPOSE:
We aim to propose a new protocol for olfaction rehabilitation after total laryngectomy based on training of sensory perception levels using the Nasal Airflow-Inducing Maneuver.
METHODS:
This is a randomized clinical trial including patients undergoing total laryngectomy between March 2010 and March 2019. Patients with nasal or oral abnormalities, prior olfaction impairment, a muco-ciliary transport time higher than 30 min, positive history for feeding, and neurological disorders were excluded. Thirty-three patients were enrolled and were randomized into two groups: an Experimental group, submitted to the new protocol (olfactory perception rehabilitation after total laryngectomy-OPRAT) and a Control group that did not receive any treatment. Subjective Olfactometry, Chemosensory Complaints Score, and University of Washington Quality of Life version 4 questionnaires were used to assess the outcomes before and after treatment, and at 3-month, 6-month, and 10-month follow-up.
RESULTS:
Among the 33 patients included (32 men and 1 woman; mean age, 67.94 ± 5.64 years), 17 were subjected to olfaction rehabilitation and 16 did not receive any treatment. At baseline evaluation, there were not significant differences between the two groups. At the end of treatment, the rehabilitated group improved their olfaction capability significantly. Such improvement remained stable over time, and after 10 months, only the Experimental group had significant improvements in all outcome measures.
CONCLUSIONS:
The OPRAT may guarantee excellent results in the short- and long-term time with positive effects on the Quality of Life.
KW - Head and neck surgery
KW - Olfaction
KW - Quality of life
KW - Rehabilitation
KW - Rhinology
KW - Total laryngectomy
KW - Head and neck surgery
KW - Olfaction
KW - Quality of life
KW - Rehabilitation
KW - Rhinology
KW - Total laryngectomy
UR - http://hdl.handle.net/10807/150086
U2 - 10.1007/s00405-020-05918-8
DO - 10.1007/s00405-020-05918-8
M3 - Article
SN - 1434-4726
SP - 2095
EP - 2105
JO - EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY AND HEAD & NECK
JF - EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY AND HEAD & NECK
ER -