Occurrence and characterization of Pain in immune-mediated neuropathies: a multicentre prospective study

Luca Padua, Costanza Pazzaglia, Pietro Caliandro, Giuseppe Granata, Pietro Attilio Tonali, C. Briani, E. N. Orazio

Risultato della ricerca: Contributo in rivistaArticolo in rivista

11 Citazioni (Scopus)


Background:  Pain is a common symptom of peripheral neuropathies that may severely affect patients’ Quality of Life. Pain questionnaires, based on verbal descriptors, are a useful way to investigate it. Methods:  We performed a multicentre study through validated measures to characterize pain in a sample of consecutive patients affected by immune-mediated neuropathies. Results:  Ninety-three patients were enrolled in 16 Italian centres. Based on the numeric rating scale, almost half of the patients complained of moderate pain and one-third of the patients severe pain. Overall, up to 50% of our patients with immune-mediated neuropathies complained of neuropathic pain. The most common neuropathic symptoms were paraesthesia/dysesthesia and superficial spontaneous pain. Surprisingly, also patients with neuropathies commonly thought to be painless (such as multifocal motor neuropathy) reported discomfort and painful symptoms. Conclusions:  Pain questionnaires should be considered in the clinical evaluation of immune-mediated neuropathies, also when evaluating therapy efficacy, because they may provide clinicians with useful information on painful symptoms and patients’ quality of life.
Lingua originaleEnglish
pagine (da-a)177-183
Numero di pagine7
Stato di pubblicazionePubblicato - 2011


  • immune-mediated neuropathies
  • neuropathic pain
  • pain questionnaire
  • peripheral nervous system

Fingerprint Entra nei temi di ricerca di 'Occurrence and characterization of Pain in immune-mediated neuropathies: a multicentre prospective study'. Insieme formano una fingerprint unica.

Cita questo