Abstract
Identification of chronic excessive alcohol consumption in living and deceased individuals is a fundamental task in forensic pathology. Reliable methods for post-mortem diagnosis of chronic alcohol abuse are required because morphological findings are unspecific and ante-mortem data are often unreliable. In clinical practice, several biochemical markers indirectly demonstrating chronic alcohol abuse are employed, but thus far these methods have not been used in routine post-mortem investigations. We reviewed publications in which these markers have been applied to autopsy material. Based on this review, some of these biochemical parameters are useful in post-mortem diagnostics, although further systematic research is required. © 2008 Elsevier Ireland Ltd. All rights reserved.
Lingua originale | English |
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pagine (da-a) | 229-235 |
Numero di pagine | 7 |
Rivista | Legal Medicine |
Volume | 10 |
DOI | |
Stato di pubblicazione | Pubblicato - 2008 |
Keywords
- 5 hydroxytryptophol
- Alcoholism
- Biological Markers
- Bone Marrow
- Brain
- Esters
- Fatty Acids
- Forensic Toxicology
- Glucuronates
- Glycerophospholipids
- Hair
- Humans
- Hydroxyindoleacetic Acid
- Hydroxytryptophol
- Liver
- Muscle, Skeletal
- Transferrin
- Vitreous Body
- alcohol consumption
- alcohol derivative
- autopsy
- biochemical marker
- carbohydrate deficient transferrin
- ethylglucuronide
- fatty acid ester
- forensic pathology
- glucuronide
- human
- phosphatidylethanol, alcohol abuse
- review, Adipose Tissue