Obesity and kidney disease: Beyond the hyperfiltration

Carmine Cardillo, Salvatore Nistico', A. Mascali, O. Franzese, S. Nisticò, U. Campia, D. Lauro, N. Di Daniele, M. Tesauro

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

10 Citazioni (Scopus)

Abstract

In industrialized countries, overweight and obesity account for approximately 13.8% and 24.9% of the kidney disease observed in men and women, respectively. Moreover, obesity-associated glomerulopathy is now considered as "an emerging epidemic." Kidney function can be negatively impacted by obesity through several mechanisms, either direct or indirect. While it is well established that obesity represents the leading risk factor for type 2 diabetes and hypertension, awareness that obesity is associated with direct kidney damage independently of hypertension and diabetes is still not widespread. In this paper we will discuss the emerging role of adipose tissue, particularly in the visceral depot, in obesity-induced chronic kidney damage.
Lingua originaleEnglish
pagine (da-a)354-363
Numero di pagine10
RivistaInternational Journal of Immunopathology and Pharmacology
Volume29
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • Immunology
  • Immunology and Allergy
  • Pharmacology
  • hyperfiltration
  • kidney disease
  • obesity

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