Nutritional support in acute pancreatitis: from physiopathology to practice. An evidence-based approach

Emanuele Rinninella*, M. G. Annetta, Maria Giuseppina Annetta, M. L. Serricchio, Michele Lorenzo Serricchio, A. A. Dal Lago, Antonio Angelo Dal Lago, Giacinto Abele Donato Miggiano, Maria Cristina Mele

*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivistaArticolo in rivista

13 Citazioni (Scopus)


Acute Pancreatitis (AP) is a potentially fatal syndrome, associated with a hyper-catabolic state as well as early and late complications that may lead to multi-organ failure and death. Clinical researches produced in recent years suggest that acute pancreatitis may benefit from early oral or enteral nutrition. Nevertheless, many clinicians still believe erroneously that fasting – particularly in the early phase – may reduce AP complications and mortality. The goal of our review is to demonstrate that such false belief may harm the patients and that the whole management paradigm must change, adopting a more rational, evidence-based approach. First, we will describe AP physiopathology and the clinical assessment of its severity. Then we will discuss evidence-based data supporting early oral or enteral nutrition in AP. Finally, we will offer some practice recommendations as regards nutritional support.
Lingua originaleEnglish
pagine (da-a)421-432
Numero di pagine12
RivistaEuropean Review for Medical and Pharmacological Sciences
Stato di pubblicazionePubblicato - 2017


  • Acute pancreatitis
  • Enteral nutrition
  • Parenteral nutrition
  • Starvation


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