Nucleotide diversity and population differentiation of the melanocortin 1 receptor gene, MC1R

Sa Savage; Gerstenblith; Am Goldstein; L Mirabello; Mc Fargnoli; Ketty Peris; Mt Landi

doi:10.1186/1471-2156-9-31

Nucleotide diversity and population differentiation of the melanocortin 1 receptor gene, MC1R

Sa Savage, Gerstenblith, Am Goldstein, L Mirabello, Mc Fargnoli, Ketty Peris, Mt Landi

Risultato della ricerca: Contributo in rivista › Articolo in rivista

26 Citazioni (Scopus)

Abstract

The melanocortin 1 receptor gene (MC1R) is responsible for normal pigment variation in humans and is highly polymorphic with numerous population-specific alleles. Some MC1R variants have been associated with skin cancer risk.

Lingua originale	English
pagine (da-a)	31-31
Numero di pagine	1
Rivista	BMC Medical Genetics
Volume	9
DOI	https://doi.org/10.1186/1471-2156-9-31
Stato di pubblicazione	Pubblicato - 2008

Keywords

Alleles
Base Sequence
Gene Frequency
Genetic Predisposition to Disease
Genetic Variation
Humans
Melanoma
Polymorphism, Single Nucleotide
Receptor, Melanocortin, Type 1
Selection, Genetic
Skin Neoplasms
Skin Pigmentation

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title = "Nucleotide diversity and population differentiation of the melanocortin 1 receptor gene, MC1R",

abstract = "The melanocortin 1 receptor gene (MC1R) is responsible for normal pigment variation in humans and is highly polymorphic with numerous population-specific alleles. Some MC1R variants have been associated with skin cancer risk.",

keywords = "Alleles, Base Sequence, Gene Frequency, Genetic Predisposition to Disease, Genetic Variation, Humans, Melanoma, Polymorphism, Single Nucleotide, Receptor, Melanocortin, Type 1, Selection, Genetic, Skin Neoplasms, Skin Pigmentation, Alleles, Base Sequence, Gene Frequency, Genetic Predisposition to Disease, Genetic Variation, Humans, Melanoma, Polymorphism, Single Nucleotide, Receptor, Melanocortin, Type 1, Selection, Genetic, Skin Neoplasms, Skin Pigmentation",

author = "Sa Savage and Gerstenblith and Am Goldstein and L Mirabello and Mc Fargnoli and Ketty Peris and Mt Landi",

year = "2008",

doi = "10.1186/1471-2156-9-31",

language = "English",

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journal = "BMC Medical Genetics",

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T1 - Nucleotide diversity and population differentiation of the melanocortin 1 receptor gene, MC1R

AU - Savage, Sa

AU - Gerstenblith,

AU - Goldstein, Am

AU - Mirabello, L

AU - Fargnoli, Mc

AU - Peris, Ketty

AU - Landi, Mt

PY - 2008

Y1 - 2008

N2 - The melanocortin 1 receptor gene (MC1R) is responsible for normal pigment variation in humans and is highly polymorphic with numerous population-specific alleles. Some MC1R variants have been associated with skin cancer risk.

AB - The melanocortin 1 receptor gene (MC1R) is responsible for normal pigment variation in humans and is highly polymorphic with numerous population-specific alleles. Some MC1R variants have been associated with skin cancer risk.

KW - Alleles

KW - Base Sequence

KW - Gene Frequency

KW - Genetic Predisposition to Disease

KW - Genetic Variation

KW - Humans

KW - Melanoma

KW - Polymorphism, Single Nucleotide

KW - Receptor, Melanocortin, Type 1

KW - Selection, Genetic

KW - Skin Neoplasms

KW - Skin Pigmentation

KW - Alleles

KW - Base Sequence

KW - Gene Frequency

KW - Genetic Predisposition to Disease

KW - Genetic Variation

KW - Humans

KW - Melanoma

KW - Polymorphism, Single Nucleotide

KW - Receptor, Melanocortin, Type 1

KW - Selection, Genetic

KW - Skin Neoplasms

KW - Skin Pigmentation

UR - http://hdl.handle.net/10807/57530

U2 - 10.1186/1471-2156-9-31

DO - 10.1186/1471-2156-9-31

M3 - Article

SN - 1471-2350

VL - 9

SP - 31

EP - 31

JO - BMC Medical Genetics

JF - BMC Medical Genetics

ER -

Nucleotide diversity and population differentiation of the melanocortin 1 receptor gene, MC1R

Abstract

Keywords

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