Novel ultrasound joint selection methods using a reduced joint number demonstrate inflammatory improvement when compared to existing methods and disease activity score at 28 joints

Maria Antonietta D'Agostino, York Kiat Tan, John C. Allen, Weng Kit Lye, Philip G. Conaghan, Li-Ching Chew, Julian Thumboo

Risultato della ricerca: Contributo in rivistaArticolo in rivista

8 Citazioni (Scopus)

Abstract

Objective. A pilot study testing novel ultrasound (US) joint-selection methods in rheumatoid arthritis. Methods. Responsiveness of novel [individualized US (IUS) and individualized composite US (ICUS)] methods were compared with existing US methods and the Disease Activity Score at 28 joints (DAS28) for 12 patients followed for 3 months. IUS selected up to 7 and 12 most ultrasonographically inflamed joints, while ICUS additionally incorporated clinically symptomatic joints. Results. The existing, IUS, and ICUS methods' standardized response means were -0.39, -1.08, and -1.11, respectively, for 7 joints; -0.49, -1.00, and -1.16, respectively, for 12 joints; and -0.94 for DAS28. Conclusion. Novel methods effectively demonstrate inflammatory improvement when compared with existing methods and DAS28.
Lingua originaleEnglish
pagine (da-a)34-37
Numero di pagine4
RivistaTHE JOURNAL OF RHEUMATOLOGY
Volume43
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • Rheumatoid arthritis
  • Ultrasonography, Doppler
  • Ultrasound
  • Aged
  • Antirheumatic Agents
  • Arthritis, Rheumatoid
  • Cohort Studies
  • Disease Progression
  • Female
  • Hospitals, General
  • Humans
  • Joints
  • Male
  • Middle Aged
  • Pain Measurement
  • Patient Selection
  • Pilot Projects
  • Range of Motion, Articular
  • Risk Assessment
  • Severity of Illness Index
  • Singapore
  • Synovitis

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