Novel biomarkers to assess the risk for acute coronary syndrome: beyond troponins

Andrea Piccioni, Federico Valletta, Christian Zanza, Alessandra Esperide, Francesco Franceschi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Current diagnostic biomarkers for ACS are mainly represented by troponin I and troponin T. Dosing of these two molecules often leads to false positive results, since their plasma levels can increase in several different systemic settings. Therefore, identification of new markers able to detect patients with acute coronary syndromes is an emerging priority. On this view, many studies have been performed on different microRNAs, mitochondrial peptides, inflammatory cytokines and adhesion molecules with very promising results. Besides their introduction in screening programs, further studies are now needed in the acute setting, beyond or in association with troponin levels. This will help to better discriminate the real occurrence of an ACS in many patients accessing the emergency department for chest pain.
Lingua originaleEnglish
pagine (da-a)1193-1199
Numero di pagine7
RivistaINTERNAL AND EMERGENCY MEDICINE
Volume15
DOI
Stato di pubblicazionePubblicato - 2020

Keywords

  • Acute coronary syndrome
  • Adhesion molecules
  • Mitochondrial peptides
  • Cytokines
  • MicroRNAs
  • Biomarkers

Fingerprint

Entra nei temi di ricerca di 'Novel biomarkers to assess the risk for acute coronary syndrome: beyond troponins'. Insieme formano una fingerprint unica.

Cita questo