Non-invasive three-dimensional electro-anatomical imaging of the site of origin of outflow tract ventricular arrhythmias with magnetocardiographic mapping

G Lombardi, Anna Rita Sorbo, Maria Grazia Guida, L La Brocca, Riccardo Fenici, Donatella Brisinda

Risultato della ricerca: Contributo in rivistaAbstract

Abstract

Ventricular arrhythmias (VAs) with left bundle-branch-block and inferior axis morphology (LBBB-IA), suggestive of outflow tract (OT) origin, are a challenge in sports medicine because they can be benign or expression of a silent cardiomyopathy. Non-invasive classification is essential to plan ablation strategy if required. We aimed to evaluating magnetocardiographic (MCG) discrimination of OT-VAs site of origin (SoO). MCG and ECG data of 26 sports activity practitioners, with OT-VAs were analyzed. OT-VAs-SoO was classified with discriminant analysis (DA) of 8 MCG parameters and with invasively-validated ECG algorithms. MCG inverse source-localization merged with magnetic resonance (CMR) provided three-dimensional electro-anatomical imaging (MCG 3D-EAI). ECG classification was univocal in 73%. MCG-DA differentiated right ventricular OT from aortic sinus cusp VAs, with 94.7% accuracy. MCG 3D-EAI confirmed OT-VAs-SoO in CMR images. In cases undergoing ablation, MCG 3D-EAI was confirmed by CARTO 3D-EAI. MCG-DA improves non-invasive classification of OT-VAs-SoO. Further comparison with interventional results is required.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaICMJE
Volume2017
DOI
Stato di pubblicazionePubblicato - 2017
Pubblicato esternamente

Keywords

  • magnetocardiographic mapping
  • outflow tract ventricular arrhythmias

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