TY - JOUR
T1 - Non-Ceruloplasmin Copper Distinguishes A Distinct Subtype of Alzheimer's Disease: A Study of EEG-Derived Brain Activity
AU - Tecchio, Franca
AU - Vecchio, Fabrizio
AU - Ventriglia, Mariacarla
AU - Porcaro, Camillo
AU - Miraglia, Francesca
AU - Siotto, Mariacristina
AU - Rossini, Paolo Maria
AU - Rongioletti, Mauro
AU - Squitti, Rosanna
PY - 2016
Y1 - 2016
N2 - Meta-analyses show that percentages of non-Cp-Cu-copper that is not bound to ceruloplasmin (also known as 'free' copper)-in serum are higher in Alzheimer's disease (AD) patients. Genetic heterogeneity in AD patients stratified on the basis of non-Cp-Cu cut-off sustains the existence of a copper AD metabolic subtype. Non-Cp-Cu abnormalities correlated with alterations of electroencephalographic rhythms (EEG).
AB - Meta-analyses show that percentages of non-Cp-Cu-copper that is not bound to ceruloplasmin (also known as 'free' copper)-in serum are higher in Alzheimer's disease (AD) patients. Genetic heterogeneity in AD patients stratified on the basis of non-Cp-Cu cut-off sustains the existence of a copper AD metabolic subtype. Non-Cp-Cu abnormalities correlated with alterations of electroencephalographic rhythms (EEG).
KW - Non-Ceruloplasmin
KW - Non-Ceruloplasmin
UR - http://hdl.handle.net/10807/92782
U2 - 10.2174/1567205013666160603001131
DO - 10.2174/1567205013666160603001131
M3 - Article
SN - 1567-2050
VL - 13
SP - 1374
EP - 1384
JO - Current Alzheimer Research
JF - Current Alzheimer Research
ER -