Non-Ceruloplasmin Copper Distinguishes A Distinct Subtype of Alzheimer's Disease: A Study of EEG-Derived Brain Activity

Fabrizio Vecchio, Francesca Miraglia, Paolo Maria Rossini, Franca Tecchio, Mariacarla Ventriglia, Camillo Porcaro, Mariacristina Siotto, Mauro Rongioletti, Rosanna Squitti

Risultato della ricerca: Contributo in rivistaArticolo in rivista

19 Citazioni (Scopus)

Abstract

Meta-analyses show that percentages of non-Cp-Cu-copper that is not bound to ceruloplasmin (also known as 'free' copper)-in serum are higher in Alzheimer's disease (AD) patients. Genetic heterogeneity in AD patients stratified on the basis of non-Cp-Cu cut-off sustains the existence of a copper AD metabolic subtype. Non-Cp-Cu abnormalities correlated with alterations of electroencephalographic rhythms (EEG).
Lingua originaleEnglish
pagine (da-a)1374-1384
Numero di pagine11
RivistaCurrent Alzheimer Research
Volume13
Stato di pubblicazionePubblicato - 2016

Keywords

  • Non-Ceruloplasmin

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