TY - JOUR
T1 - NM23 in ovarian cancer: Correlation with clinicopathological and biochemical parameters
AU - Ferrandina, Maria Gabriella
AU - Scambia, Giovanni
AU - Marone, Maria
AU - Benedetti Panici, Pierluigi
AU - Giannitelli, Cecilia
AU - Pernisco, Stefania
AU - Coronetta, Ferdinando
AU - Mancuso, Maurizio Stefano
PY - 1996
Y1 - 1996
N2 - The nm23 gene, originally identified by differential hybridization between two murine melanoma cell lines endowed with different metastatic potential, has been reported to play a metastasis suppressor function in different experimentale models. Several studies have focused on the favorable clinical significance of nm23 overexpression as a metastasis suppessor marker in breast, prostate, and gastric cancer, although conflicting data have been reported. In our laboratory, the immunohistochemical expression of nm23-H1 has been Investigated in a series of 106 primary human ovarian carcinomas in order to determine its possible association with clinicopatholoigcla characteristics and epidermal growth factors receptor (EGFR).
AB - The nm23 gene, originally identified by differential hybridization between two murine melanoma cell lines endowed with different metastatic potential, has been reported to play a metastasis suppressor function in different experimentale models. Several studies have focused on the favorable clinical significance of nm23 overexpression as a metastasis suppessor marker in breast, prostate, and gastric cancer, although conflicting data have been reported. In our laboratory, the immunohistochemical expression of nm23-H1 has been Investigated in a series of 106 primary human ovarian carcinomas in order to determine its possible association with clinicopatholoigcla characteristics and epidermal growth factors receptor (EGFR).
KW - nm23,ovarian cancer
KW - nm23,ovarian cancer
UR - http://hdl.handle.net/10807/162569
U2 - 10.1111/j.1749-6632.1996.tb16271.x
DO - 10.1111/j.1749-6632.1996.tb16271.x
M3 - Article
SN - 0077-8923
VL - 784
SP - 509
EP - 512
JO - Annals of the New York Academy of Sciences
JF - Annals of the New York Academy of Sciences
ER -