NM23 in ovarian cancer: Correlation with clinicopathological and biochemical parameters

Maria Gabriella Ferrandina; Giovanni Scambia; Maurizio Stefano Mancuso

doi:10.1111/j.1749-6632.1996.tb16271.x

NM23 in ovarian cancer: Correlation with clinicopathological and biochemical parameters

Maria Gabriella Ferrandina, Giovanni Scambia, Maurizio Stefano Mancuso

Risultato della ricerca: Contributo in rivista › Articolo in rivista

2 Citazioni (Scopus)

Abstract

The nm23 gene, originally identified by differential hybridization between two murine melanoma cell lines endowed with different metastatic potential, has been reported to play a metastasis suppressor function in different experimentale models. Several studies have focused on the favorable clinical significance of nm23 overexpression as a metastasis suppessor marker in breast, prostate, and gastric cancer, although conflicting data have been reported. In our laboratory, the immunohistochemical expression of nm23-H1 has been Investigated in a series of 106 primary human ovarian carcinomas in order to determine its possible association with clinicopatholoigcla characteristics and epidermal growth factors receptor (EGFR).

Lingua originale	English
pagine (da-a)	509-512
Numero di pagine	4
Rivista	Annals of the New York Academy of Sciences
Volume	784
DOI	https://doi.org/10.1111/j.1749-6632.1996.tb16271.x
Stato di pubblicazione	Pubblicato - 1996

Keywords

nm23,ovarian cancer

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10.1111/j.1749-6632.1996.tb16271.x

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title = "NM23 in ovarian cancer: Correlation with clinicopathological and biochemical parameters",

abstract = "The nm23 gene, originally identified by differential hybridization between two murine melanoma cell lines endowed with different metastatic potential, has been reported to play a metastasis suppressor function in different experimentale models. Several studies have focused on the favorable clinical significance of nm23 overexpression as a metastasis suppessor marker in breast, prostate, and gastric cancer, although conflicting data have been reported. In our laboratory, the immunohistochemical expression of nm23-H1 has been Investigated in a series of 106 primary human ovarian carcinomas in order to determine its possible association with clinicopatholoigcla characteristics and epidermal growth factors receptor (EGFR).",

keywords = "nm23,ovarian cancer, nm23,ovarian cancer",

author = "Ferrandina, {Maria Gabriella} and Giovanni Scambia and Mancuso, {Maurizio Stefano}",

year = "1996",

doi = "10.1111/j.1749-6632.1996.tb16271.x",

language = "English",

volume = "784",

pages = "509--512",

journal = "Annals of the New York Academy of Sciences",

issn = "0077-8923",

publisher = "New York Academy of Sciences:Subscription Services Department, 2 East 63rd Street:New York, NY 10021:(800)843-6927, (212)838-0230, EMAIL: publications@nyas.org, INTERNET: http://www.nyas.org, Fax: (212)888-2894",

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TY - JOUR

T1 - NM23 in ovarian cancer: Correlation with clinicopathological and biochemical parameters

AU - Ferrandina, Maria Gabriella

AU - Scambia, Giovanni

AU - Mancuso, Maurizio Stefano

PY - 1996

Y1 - 1996

N2 - The nm23 gene, originally identified by differential hybridization between two murine melanoma cell lines endowed with different metastatic potential, has been reported to play a metastasis suppressor function in different experimentale models. Several studies have focused on the favorable clinical significance of nm23 overexpression as a metastasis suppessor marker in breast, prostate, and gastric cancer, although conflicting data have been reported. In our laboratory, the immunohistochemical expression of nm23-H1 has been Investigated in a series of 106 primary human ovarian carcinomas in order to determine its possible association with clinicopatholoigcla characteristics and epidermal growth factors receptor (EGFR).

AB - The nm23 gene, originally identified by differential hybridization between two murine melanoma cell lines endowed with different metastatic potential, has been reported to play a metastasis suppressor function in different experimentale models. Several studies have focused on the favorable clinical significance of nm23 overexpression as a metastasis suppessor marker in breast, prostate, and gastric cancer, although conflicting data have been reported. In our laboratory, the immunohistochemical expression of nm23-H1 has been Investigated in a series of 106 primary human ovarian carcinomas in order to determine its possible association with clinicopatholoigcla characteristics and epidermal growth factors receptor (EGFR).

KW - nm23,ovarian cancer

UR - http://hdl.handle.net/10807/162569

U2 - 10.1111/j.1749-6632.1996.tb16271.x

DO - 10.1111/j.1749-6632.1996.tb16271.x

M3 - Article

VL - 784

SP - 509

EP - 512

JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

SN - 0077-8923

ER -

NM23 in ovarian cancer: Correlation with clinicopathological and biochemical parameters

Abstract

Keywords

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