NM23 in ovarian cancer: Correlation with clinicopathological and biochemical parameters

Maria Gabriella Ferrandina, Giovanni Scambia, Maurizio Stefano Mancuso

Risultato della ricerca: Contributo in rivistaArticolo in rivista

2 Citazioni (Scopus)

Abstract

The nm23 gene, originally identified by differential hybridization between two murine melanoma cell lines endowed with different metastatic potential, has been reported to play a metastasis suppressor function in different experimentale models. Several studies have focused on the favorable clinical significance of nm23 overexpression as a metastasis suppessor marker in breast, prostate, and gastric cancer, although conflicting data have been reported. In our laboratory, the immunohistochemical expression of nm23-H1 has been Investigated in a series of 106 primary human ovarian carcinomas in order to determine its possible association with clinicopatholoigcla characteristics and epidermal growth factors receptor (EGFR).
Lingua originaleEnglish
pagine (da-a)509-512
Numero di pagine4
RivistaAnnals of the New York Academy of Sciences
Volume784
DOI
Stato di pubblicazionePubblicato - 1996

Keywords

  • nm23,ovarian cancer

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