New prediction tools and treatment for ACS patients with plaque erosion

Filippo Crea, Rocco Vergallo, Ik-Kyung Jang

Risultato della ricerca: Contributo in rivistaArticolo in rivista

1 Citazioni (Scopus)

Abstract

For decades, we have known from autopsy observations that the proximate cause of the majority of acute coronary syndromes ( ACS) is occlusive thrombosis generated by plaque rupture or, less frequently, superficial erosion. Patients with ACS caused by plaque erosion seem to have a better long-term prognosis compared to those with plaque rupture, and may be stabilized by dual antiplatelet therapy without the need for stenting in a non-trivial proportion of cases, limiting the expenses and potential complications of invasive procedures. The accurate prediction of plaque erosion and the identification of specific biomarkers that could be used at the point-of-care without the need of invasive imaging would take us a step closer to the holy grail of precision medicine in patients with ACS.
Lingua originaleEnglish
pagine (da-a)45-51
Numero di pagine7
RivistaATHEROSCLEROSIS
DOI
Stato di pubblicazionePubblicato - 2021

Keywords

  • Acute coronary syndrome
  • Optical coherence tomography
  • Tailored therapy
  • Precision medicine
  • Prediction tools
  • Plaque erosion

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