Neoadjuvant Chemotherapy in Breast Cancer: An Advanced Personalized Multidisciplinary Prehabilitation Model (APMP-M) to Optimize Outcomes

Alba Di Leone, Daniela Andreina Terribile, Stefano Magno, Alejandro Martin Sanchez, Lorenzo Scardina, Elena Jane Mason, Sabatino D’Archi, Claudia Maggiore, Cristina Rossi, Annalisa Di Micco, Stefania Carnevale, Ida Paris, Fabio Marazzi, Valeria Masiello, Armando Orlandi, Antonella Palazzo, Alessandra Fabi, Riccardo Masetti, Gianluca Franceschini

Risultato della ricerca: Contributo in rivistaArticolo in rivista


Neoadjuvant chemotherapy is increasingly being employed in the management of breast cancer patients. Efforts and resources have been devoted over the years to the search for an optimal strategy that can improve outcomes in the neoadjuvant setting. Today, a multidisciplinary approach with the application of evidence-based medicine is considered the gold standard for the improvement of oncological results and patient satisfaction. However, several clinical complications and psychological issues due to various factors can arise during neoadjuvant therapy and undermine outcomes. To ensure that health care needs are adequately addressed, clinicians must consider that women with breast cancer have a high risk of developing “unmet needs” during treatment, and often require a clinical intervention or additional care resources to limit possible complications and psychological issues that can occur during neoadjuvant treatment. This work describes a multidisciplinary model developed at “Fondazione Policlinico Universitario Agostino Gemelli” (FPG) in Rome in an effort to optimize treatment, ease the application of evidence-based medicine, and improve patient quality of life in the neoadjuvant setting. In developing our model, our main goal was to adequately meet patient needs while preventing high levels of distress.
Lingua originaleEnglish
pagine (da-a)324-324
Numero di pagine14
RivistaJournal of Personalized Medicine
Stato di pubblicazionePubblicato - 2021


  • breast cancer
  • evidence-based medicine
  • multidisciplinary treatment
  • neoadjuvant chemotherapy
  • oncological outcomes
  • patient quality of life
  • personalized treatment


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