Nasal secretion specific IgE in rhinitis patients

Eleonora Nucera, Alessandro Milani, Domenico Schiavino, Giampiero Patriarca, V Di Rienzo, Alberto Romano, S Pellegrino, G Fais

Risultato della ricerca: Contributo in rivistaArticolo in rivista

5 Citazioni (Scopus)

Abstract

Forty-five subjects with rhinitis of suspected allergic origin underwent immune and allergy testing including skin-tests and immuno-enzymatic assay of serum and nasal secretion specific IgE (RAST). Nasal secretion was collected using a cotton tampon inserted in both middle meati. A statistical analysis comparing the results of skin-tests and serum RAST was performed: the results obtained with these two techniques were very homogeneous (86.7% accuracy). An overall concordance (82.2%) was also observed by comparing skin-tests and nasal secretion RAST. Finally, the results of serum and nasal secretion RAST were compared: in this case totally superimposed data were reported (overall accuracy: 93.3%). In all cases the comparison between RAST classes in serum and nasal secretion was carried out: the difference between the semiquantitative evaluation of reaginic concentration classes using these two methods is not statistically significant (chi-square test). This technique of nasal secretion collection is simple and with no risk involved.
Lingua originaleEnglish
pagine (da-a)1-4
Numero di pagine4
RivistaAllergologia et Immunopathologia
Volume18
Stato di pubblicazionePubblicato - 1990

Keywords

  • Adolescent
  • Adult
  • Body Fluids
  • Child
  • Female
  • Humans
  • Immunoglobulin E
  • Male
  • Middle Aged
  • Nasal Mucosa
  • Radioallergosorbent Test
  • Rhinitis
  • Skin Tests
  • Specimen Handling

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