Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia

Antonio Ruggiero; Gabriella De Rosa; Daniela Rizzo; A Leo; Palma Maurizi; Alessia De Nisco; Francesca Vendittelli; Cecilia Zuppi; Alvaro Mordente; Riccardo Riccardi

doi:10.1007/s10147-012-0458-9

Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia

Antonio Ruggiero^*, Gabriella De Rosa, Daniela Rizzo, A Leo, Palma Maurizi, Alessia De Nisco, Francesca Vendittelli, Cecilia Zuppi, Alvaro Mordente, Riccardo Riccardi

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo

35 Citazioni (Scopus)

Abstract

Despite significant improvements in the prognosis of childhood acute lymphoblastic leukaemia (ALL), the risk of anthracycline-induced cardiovascular disease remains a major concern. This study was designed to investigate the role of the myocardial performance index (MPI) and serum concentrations of biomarkers (cTnT and NT-pro-BNP) in the early detection of subclinical anthracycline-induced functional alterations in children with ALL.

Lingua originale	Inglese
pagine (da-a)	927-933
Numero di pagine	7
Rivista	International Journal of Clinical Oncology
Volume	18
Numero di pubblicazione	5
DOI	https://doi.org/10.1007/s10147-012-0458-9
Stato di pubblicazione	Pubblicato - 2013

All Science Journal Classification (ASJC) codes

Chirurgia
Ematologia
Oncologia

Keywords

Myocardial performance index
biochemical markers
cardiotoxicity
doxorubicin

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10.1007/s10147-012-0458-9

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Ruggiero, A., De Rosa, G., Rizzo, D., Leo, A., Maurizi, P., De Nisco, A., Vendittelli, F., Zuppi, C., Mordente, A., & Riccardi, R. (2013). Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia. International Journal of Clinical Oncology, 18(5), 927-933. https://doi.org/10.1007/s10147-012-0458-9

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abstract = "Despite significant improvements in the prognosis of childhood acute lymphoblastic leukaemia (ALL), the risk of anthracycline-induced cardiovascular disease remains a major concern. This study was designed to investigate the role of the myocardial performance index (MPI) and serum concentrations of biomarkers (cTnT and NT-pro-BNP) in the early detection of subclinical anthracycline-induced functional alterations in children with ALL.",

keywords = "Myocardial performance index, biochemical markers, cardiotoxicity, doxorubicin, Myocardial performance index, biochemical markers, cardiotoxicity, doxorubicin",

author = "Antonio Ruggiero and {De Rosa}, Gabriella and Daniela Rizzo and A Leo and Palma Maurizi and {De Nisco}, Alessia and Francesca Vendittelli and Cecilia Zuppi and Alvaro Mordente and Riccardo Riccardi",

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Ruggiero, A , De Rosa, G, Rizzo, D, Leo, A, Maurizi, P, De Nisco, A, Vendittelli, F, Zuppi, C, Mordente, A & Riccardi, R 2013, 'Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia', International Journal of Clinical Oncology, vol. 18, n. 5, pagg. 927-933. https://doi.org/10.1007/s10147-012-0458-9

TY - JOUR

T1 - Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia

AU - Ruggiero, Antonio

AU - De Rosa, Gabriella

AU - Rizzo, Daniela

AU - Leo, A

AU - Maurizi, Palma

AU - De Nisco, Alessia

AU - Vendittelli, Francesca

AU - Zuppi, Cecilia

AU - Mordente, Alvaro

AU - Riccardi, Riccardo

PY - 2013

Y1 - 2013

N2 - Despite significant improvements in the prognosis of childhood acute lymphoblastic leukaemia (ALL), the risk of anthracycline-induced cardiovascular disease remains a major concern. This study was designed to investigate the role of the myocardial performance index (MPI) and serum concentrations of biomarkers (cTnT and NT-pro-BNP) in the early detection of subclinical anthracycline-induced functional alterations in children with ALL.

AB - Despite significant improvements in the prognosis of childhood acute lymphoblastic leukaemia (ALL), the risk of anthracycline-induced cardiovascular disease remains a major concern. This study was designed to investigate the role of the myocardial performance index (MPI) and serum concentrations of biomarkers (cTnT and NT-pro-BNP) in the early detection of subclinical anthracycline-induced functional alterations in children with ALL.

KW - Myocardial performance index

KW - biochemical markers

KW - cardiotoxicity

KW - doxorubicin

KW - Myocardial performance index

KW - biochemical markers

KW - cardiotoxicity

KW - doxorubicin

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JO - International Journal of Clinical Oncology

JF - International Journal of Clinical Oncology

IS - 5

ER -

Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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