Myocardial performance index and biochemical markers for early detection of doxorubicin-induced cardiotoxicity in children with acute lymphoblastic leukaemia

Antonio Ruggiero, Gabriella De Rosa, Palma Maurizi, Alvaro Mordente, Daniela Rizzo, Alessia De Nisco, Francesca Vendittelli, Cecilia Zuppi, Riccardo Riccardi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

35 Citazioni (Scopus)

Abstract

Despite significant improvements in the prognosis of childhood acute lymphoblastic leukaemia (ALL), the risk of anthracycline-induced cardiovascular disease remains a major concern. This study was designed to investigate the role of the myocardial performance index (MPI) and serum concentrations of biomarkers (cTnT and NT-pro-BNP) in the early detection of subclinical anthracycline-induced functional alterations in children with ALL.
Lingua originaleEnglish
pagine (da-a)927-933
Numero di pagine7
RivistaInternational Journal of Clinical Oncology
Volume18
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • Myocardial performance index
  • biochemical markers
  • cardiotoxicity
  • doxorubicin

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