MYO-MRI diagnostic protocols in genetic myopathies

Jodi Warman Chardon, Jordi Díaz-Manera, Giorgio Tasca, Carsten G. Bönnemann, David Gómez-Andrés, Arend Heerschap, Eugenio Mercuri, Francesco Muntoni, Anna Pichiecchio, Enzo Ricci, Maggie C. Walter, Michael Hanna, Heinz Jungbluth, Jasper M. Morrow, Roberto Fernández Torrón, Bjarne Udd, John Vissing, Tarek Yousry, Susana Quijano-Roy, Volker StraubRobert Y Carlier

Risultato della ricerca: Contributo in rivistaArticolo in rivista

15 Citazioni (Scopus)


Whole-body magnetic resonance imaging has emerged as a useful imaging tool in diagnosing and characterizing the progression of myopathies and muscular dystrophies. Whole-body MRI indications and diagnostic efficacy are becoming better defined with the increasing number of cases, publications and discussions within multidisciplinary working groups. Advanced Whole-body MRI protocols are rapid, lower cost, and well-tolerated by patients. Accurate interpretation of muscle Whole-body MRI requires a detailed knowledge of muscle anatomy and differential pattern of involvement in muscle diseases. With the surge in recently identified novel genetic myopathies, Whole-body MRI will become increasingly useful for phenotypic validation of genetic variants of unknown significance. In addition, Whole-body MRI will be progressively used as a biomarker for disease progression and quantify response to therapy with the emergence of novel disease modifying treatments. This review outlines Whole-body MRI indications and updates refined protocols and provides a comprehensive overview of the diagnostic utility and suggested methodology of Whole-body MRI for pediatric and adult patients with muscle diseases.
Lingua originaleEnglish
pagine (da-a)827-841
Numero di pagine15
RivistaNeuromuscular Disorders
Stato di pubblicazionePubblicato - 2019


  • Congenital myopathy
  • Inflammatory myopathy
  • Inherited myopathy
  • Limb girdle muscular dystrophy
  • Magnetic resonance imaging
  • Whole-body MRI


Entra nei temi di ricerca di 'MYO-MRI diagnostic protocols in genetic myopathies'. Insieme formano una fingerprint unica.

Cita questo