Mydriasis induced by sub-Tenon's ropivacaine: injection in patients undergoing strabismus surgery

Gustavo Savino, Vittoria Perrotta, Daniela Colucci, Laura Balia, Rossella Garra, Sergio Petroni, Emilio Balestrazzi, Maria Sammartino Sinicalco, Alessandra Mastrocola

Risultato della ricerca: Contributo in rivistaArticolo in rivista

6 Citazioni (Scopus)


PURPOSE:To investigate the effects of sub-Tenon's capsule ropivacaine injection on pupillary diameter in strabismus surgery. METHODS: A total of 16 patients were randomly assigned to 2 groups. The ropivacaine group (R) received sub-Tenon's ropivacaine 1% (2.5-3 mL) injections. In the control group (C), general anesthesia was induced and a saline solution (2.5-3 mL) was injected in the sub-Tenon's capsule. Pupillary diameter was measured at baseline and 2 and 5 minutes from the injections. The effects of the injections were expressed as a ratio of final (5 minutes) versus basal diameter. RESULTS: A significant mydriasis occurred in the ropivacaine group when compared with the control group (Group R vs Group C ratio = 2.32, p < 0.0001) or with unoperated fellow eye (R vs unoperated eye ratio = 2.29, p < 0.0001). CONCLUSIONS: Ropivacaine in the sub-Tenon's capsule induces a mydriasis probably related to a pharmacological ciliary ganglion block. Copyright 2010 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.
Lingua originaleEnglish
pagine (da-a)124-126
Numero di pagine3
RivistaJournal of AAPOS
Stato di pubblicazionePubblicato - 2010


  • strabismus
  • sub-Tenon's ropivacaine injection


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