Myasthenia gravis with presynaptic neurophysiological signs: Two case reports and literature review

Amelia Evoli, Paolo Emilio Alboini, Valentina Damato, Raffaele Iorio, Marco Luigetti

Risultato della ricerca: Contributo in rivistaArticolo in rivista

5 Citazioni (Scopus)

Abstract

Abstract The distinction between myasthenia gravis and Lambert-Eaton myasthenic syndrome is based on clinical, neurophysiological and immunological features. We hereby report two cases with a clinical diagnosis of myasthenia gravis and neurophysiological features consistent with a pre-synaptic neuromuscular transmission defect. Both patients had increased anti-acetylcholine receptor antibody titres and showed a good response to cholinesterase inhibitors, along with a >100% facilitation of the compound muscle action potential on electrophysiological studies. We provide a review of English literature studies on co-existing features of myasthenia gravis and Lambert-Eaton myasthenic syndrome, and discuss diagnostic controversies.
Lingua originaleEnglish
pagine (da-a)646-650
Numero di pagine5
RivistaNeuromuscular Disorders
Volume25
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • 3,4-diaminopyridine
  • Cholinesterase inhibitors
  • Lambert-Eaton myasthenic syndrome
  • Myasthenia gravis

Fingerprint Entra nei temi di ricerca di 'Myasthenia gravis with presynaptic neurophysiological signs: Two case reports and literature review'. Insieme formano una fingerprint unica.

Cita questo