Myasthenia gravis associated with thymoma: clinical characteristics and long-term outcome

Amelia Evoli; Anna Paola Batocchi; Mt Palmisani; Carlo Provenzano; Pietro Attilio Tonali

Myasthenia gravis associated with thymoma: clinical characteristics and long-term outcome

Amelia Evoli, Anna Paola Batocchi, Mt Palmisani, Carlo Provenzano, Pietro Attilio Tonali

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Abstract

We studied 111 myasthenic patients with thymoma followed over the last 20 years. Most patients were affected with severe myasthenia gravis (MG) and had been treated with immunosuppressive drugs. At the end of the follow-up, we observed good therapeutic results in 74% of patients, but a complete remission in only 10% of cases. The survival rate in thymoma patients was significantly lower than in nonthymoma cases. Clinical parameters, MG response to treatment and survival rate did not differ in patients with invasive and noninvasive thymic neoplasms. Patients with invasive thymoma showed slightly higher surgical mortality and a 10% incidence of tumor relapse.

Lingua originale	English
pagine (da-a)	78-82
Numero di pagine	5
Rivista	European Neurology
Volume	34
Stato di pubblicazione	Pubblicato - 1994

Keywords

Follow-Up Studies
Myasthenia Gravis
Thymectomy
Thymoma

Altri file e collegamenti

Link a IRIS PubliCatt

Fingerprint Entra nei temi di ricerca di 'Myasthenia gravis associated with thymoma: clinical characteristics and long-term outcome'. Insieme formano una fingerprint unica.

Cita questo

@article{54c2bf6e12914361a02b59dd66dd80e8,

title = "Myasthenia gravis associated with thymoma: clinical characteristics and long-term outcome",

abstract = "We studied 111 myasthenic patients with thymoma followed over the last 20 years. Most patients were affected with severe myasthenia gravis (MG) and had been treated with immunosuppressive drugs. At the end of the follow-up, we observed good therapeutic results in 74% of patients, but a complete remission in only 10% of cases. The survival rate in thymoma patients was significantly lower than in nonthymoma cases. Clinical parameters, MG response to treatment and survival rate did not differ in patients with invasive and noninvasive thymic neoplasms. Patients with invasive thymoma showed slightly higher surgical mortality and a 10% incidence of tumor relapse.",

keywords = "Follow-Up Studies, Myasthenia Gravis, Thymectomy, Thymoma, Follow-Up Studies, Myasthenia Gravis, Thymectomy, Thymoma",

author = "Amelia Evoli and Batocchi, {Anna Paola} and Mt Palmisani and Carlo Provenzano and Tonali, {Pietro Attilio}",

year = "1994",

language = "English",

volume = "34",

pages = "78--82",

journal = "European Neurology",

issn = "0014-3022",

publisher = "S Karger AG:Allschwilerstrasse 10, CH-4009 Basel Switzerland:011 41 61 3061111, EMAIL: orders@karger.ch, INTERNET: http://www.karger.com, Fax: 011 41 61 3061234",

}

TY - JOUR

T1 - Myasthenia gravis associated with thymoma: clinical characteristics and long-term outcome

AU - Evoli, Amelia

AU - Batocchi, Anna Paola

AU - Palmisani, Mt

AU - Provenzano, Carlo

AU - Tonali, Pietro Attilio

PY - 1994

Y1 - 1994

N2 - We studied 111 myasthenic patients with thymoma followed over the last 20 years. Most patients were affected with severe myasthenia gravis (MG) and had been treated with immunosuppressive drugs. At the end of the follow-up, we observed good therapeutic results in 74% of patients, but a complete remission in only 10% of cases. The survival rate in thymoma patients was significantly lower than in nonthymoma cases. Clinical parameters, MG response to treatment and survival rate did not differ in patients with invasive and noninvasive thymic neoplasms. Patients with invasive thymoma showed slightly higher surgical mortality and a 10% incidence of tumor relapse.

AB - We studied 111 myasthenic patients with thymoma followed over the last 20 years. Most patients were affected with severe myasthenia gravis (MG) and had been treated with immunosuppressive drugs. At the end of the follow-up, we observed good therapeutic results in 74% of patients, but a complete remission in only 10% of cases. The survival rate in thymoma patients was significantly lower than in nonthymoma cases. Clinical parameters, MG response to treatment and survival rate did not differ in patients with invasive and noninvasive thymic neoplasms. Patients with invasive thymoma showed slightly higher surgical mortality and a 10% incidence of tumor relapse.

KW - Follow-Up Studies

KW - Myasthenia Gravis

KW - Thymectomy

KW - Thymoma

KW - Follow-Up Studies

KW - Myasthenia Gravis

KW - Thymectomy

KW - Thymoma

UR - http://hdl.handle.net/10807/19813

M3 - Article

VL - 34

SP - 78

EP - 82

JO - European Neurology

JF - European Neurology

SN - 0014-3022

ER -