TY - JOUR
T1 - multiple viral genome search in endolabyrinthic fluids of profoundly deaf patients: possible cytomegalovirus intracochlear reactivation
AU - Di Nardo, Walter
AU - Cattani Franchi, Paola
AU - Lopizzo, Teresa
AU - Cantore, Italo
AU - Marchese, Maria Raffaella
AU - Marchetti, Simona
AU - Scorpecci, Alessandro
AU - Giannantonio, Sara
AU - Parrilla, Claudio
AU - Cianfrone, Francesca
AU - Fadda, Giovanni
AU - Paludetti, Gaetano
PY - 2009
Y1 - 2009
N2 - In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15-month-old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection.
AB - In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15-month-old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection.
KW - CYTOMEGALOVIRUS
KW - ENDOLABYRINTHIC FLUID
KW - CYTOMEGALOVIRUS
KW - ENDOLABYRINTHIC FLUID
UR - http://hdl.handle.net/10807/33229
M3 - Article
VL - 14
SP - 290
EP - 295
JO - Audioogyl & neurootology
JF - Audioogyl & neurootology
ER -