Multiple squamous cell carcinomas of the skin during long-term treatment with hydroxyurea

Clara De Simone, Cristina Guerriero, Maurizio Rotoli, Antonio Venier, Raffaele Tartaglione, B Guidi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

27 Citazioni (Scopus)

Abstract

Hydroxyurea is a chemotherapeutic agent used extensively for myeloproliferative disorders. Cutaneous side effects have been described during long-term hydroxyurea treatment. We described the occurrence of multiple squamous cell skin carcinomas in a patient treated with hydroxyurea for chronic myelogenous leukemia. The lesions were removed and the hematological therapy switched to busulfan. In a previously reported case, the development of cutaneous epithelial cancers required the discontinuation of hydroxyurea, in addition to the surgical excision of the neoplastic lesions. Since squamous cell carcinoma is a malignant cutaneous neoplasm that can metastatize, the surveillance of skin changes is advisable during hydroxyurea treatment.
Lingua originaleEnglish
pagine (da-a)114-115
Numero di pagine2
RivistaEuropean Journal of Dermatology
Volume8
Stato di pubblicazionePubblicato - 1998

Keywords

  • Aged
  • Antineoplastic Agents
  • Carcinoma, Squamous Cell
  • Face
  • Humans
  • Hydroxyurea
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive
  • Male
  • Neoplasms, Second Primary
  • Skin Neoplasms

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