MRI in uterine cancers with uncertain origin: Endometrial or cervical? Radiological point of view with review of the literature

Benedetta Gui, Michela Lupinelli, Luca Russo, Maura Miccò, Giacomo Avesani, Camilla Panico, Valerio Di Paola, Elena Rodolfino, Rosa Autorino, Maria Gabriella Ferrandina, Francesco Fanfani, Giovanni Scambia, Riccardo Manfredi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Therapeutic options and clinical management of cervical and endometrial cancers differs significantly. When clinical and histological analysis of a uterine mass are unable to differentiate between an endocervical or endometrial origin, magnetic resonance imaging (MRI) plays a pivotal role in discriminating the anatomical origin, supporting the clinician in the treatment planning. Cervical adenocarcinomas are more likely to be centered in the cervical region and involving both cervical canal and stromal ring, with possible parametrial invasion. Endometrial adenocarcinomas usually present an elongated morphology and are centered in the endometrial cavity predominantly involving endometrium and myometrium. On contrast-enhanced sequences, cervical cancers are more frequently hypervascular compared to endometrial cancers. In cases of uncertain findings, diffusion-weighted imaging (DWI) can provide additional helpful information with significantly higher apparent coefficient diffusion (ADC) values in cervical adenocarcinomas compared to endometrial adenocarci-nomas. However, even when MRI cannot precisely reveal the origin of the tumor, it provides valuable infor-mation on several prognostic factors that can help treatment planning.
Lingua originaleEnglish
pagine (da-a)110357-N/A
RivistaEuropean Journal of Radiology
Volume153
DOI
Stato di pubblicazionePubblicato - 2022

Keywords

  • Cervical cancer
  • Endometrial cancer
  • Gynaecological cancer
  • MRI
  • Uterine mass

Fingerprint

Entra nei temi di ricerca di 'MRI in uterine cancers with uncertain origin: Endometrial or cervical? Radiological point of view with review of the literature'. Insieme formano una fingerprint unica.

Cita questo